Nanomaterials toward the treatment of Alzheimer's disease: Recent advances and future trends
H Zeng, Y Qi, Z Zhang, C Liu, W Peng, Y Zhang - Chinese chemical letters, 2021 - Elsevier
Alzheimer's disease (AD) is a progressive and fatal neurodegenerative condition and the
most prevalent cause of dementia. This disease is characterized by progressive cognitive …
most prevalent cause of dementia. This disease is characterized by progressive cognitive …
Microglia and the blood–brain barrier: An external player in acute and chronic neuroinflammatory conditions
GS Gullotta, G Costantino, MA Sortino… - International Journal of …, 2023 - mdpi.com
Microglia are the resident immune cells of the central nervous system that guarantee
immune surveillance and exert also a modulating role on neuronal synaptic development …
immune surveillance and exert also a modulating role on neuronal synaptic development …
Antioxidant activity of fluoxetine and vortioxetine in a non-transgenic animal model of alzheimer's disease
Depression is a risk factor for the development of Alzheimer's disease (AD). A
neurobiological and clinical continuum exists between AD and depression, with …
neurobiological and clinical continuum exists between AD and depression, with …
Melittin and diclofenac synergistically promote wound healing in a pathway involving TGF-β1
A dysregulation of the wound healing process can lead to the development of various
intractable ulcers or excessive scar formation. Therefore it is essential to identify novel …
intractable ulcers or excessive scar formation. Therefore it is essential to identify novel …
The therapeutic potential of carnosine as an antidote against drug-induced cardiotoxicity and neurotoxicity: Focus on nrf2 pathway
Different drug classes such as antineoplastic drugs (anthracyclines, cyclophosphamide, 5-
fluorouracil, taxanes, tyrosine kinase inhibitors), antiretroviral drugs, antipsychotic, and …
fluorouracil, taxanes, tyrosine kinase inhibitors), antiretroviral drugs, antipsychotic, and …
Antioxidant properties of second-generation antipsychotics: Focus on microglia
Recent studies suggest a primary role of oxidative stress in an early phase of the
pathogenesis of schizophrenia and a strong neurobiological link has been found between …
pathogenesis of schizophrenia and a strong neurobiological link has been found between …
Gap junctions and connexins in microglia-related oxidative stress and neuroinflammation: perspectives for drug discovery
Microglia represent the immune system of the brain. Their role is central in two phenomena,
neuroinflammation and oxidative stress, which are at the roots of different pathologies …
neuroinflammation and oxidative stress, which are at the roots of different pathologies …
The role of PI3K signaling pathway in Alzheimer's disease
J Pan, Q Yao, Y Wang, S Chang, C Li, Y Wu… - Frontiers in Aging …, 2024 - frontiersin.org
Alzheimer's disease (AD) is a debilitating progressively neurodegenerative disease. The
best-characterized hallmark of AD, which is marked by behavioral alterations and cognitive …
best-characterized hallmark of AD, which is marked by behavioral alterations and cognitive …
[HTML][HTML] The therapeutic potential of carnosine: Focus on cellular and molecular mechanisms
Carnosine is a naturally occurring endogenous dipeptide composed by the ligation of β-
alanine and L-histidine performed particularly by tissues with an increased oxidative …
alanine and L-histidine performed particularly by tissues with an increased oxidative …
The therapeutic potential of novel carnosine formulations: perspectives for drug development
A Bonaccorso, A Privitera, M Grasso, S Salamone… - Pharmaceuticals, 2023 - mdpi.com
Carnosine (beta-alanyl-L-histidine) is an endogenous dipeptide synthesized via the activity
of the ATP-dependent enzyme carnosine synthetase 1 and can be found at a very high …
of the ATP-dependent enzyme carnosine synthetase 1 and can be found at a very high …