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Recent Progress in the Development of HIV-1 Protease Inhibitors for the Treatment of HIV/AIDS
HIV-1 protease inhibitors continue to play an important role in the treatment of HIV/AIDS,
transforming this deadly ailment into a more manageable chronic infection. Over the years …
transforming this deadly ailment into a more manageable chronic infection. Over the years …
Cytokines and chemokines at the crossroads of neuroinflammation, neurodegeneration, and neuropathic pain
Cytokines and chemokines are proteins that coordinate the immune response throughout
the body. The dysregulation of cytokines and chemokines is a central feature in the …
the body. The dysregulation of cytokines and chemokines is a central feature in the …
A review of the toxicity of HIV medications
AM Margolis, H Heverling, PA Pham… - Journal of medical …, 2014 - Springer
Antiretroviral therapy has changed human immunodeficiency virus (HIV) infection from a
near-certainly fatal illness to one that can be managed chronically. More patients are taking …
near-certainly fatal illness to one that can be managed chronically. More patients are taking …
Cognitive dysfunction in HIV patients despite long-standing suppression of viremia
Objective: To determine the prevalence of cognitive complaints and HIV-associated
neurocognitive disorders (HANDs) in a cohort of aviremic HIV-positive patients. To evaluate …
neurocognitive disorders (HANDs) in a cohort of aviremic HIV-positive patients. To evaluate …
Risky sexual behavior and substance use among adolescents: A meta-analysis
This study presents the results of a meta-analysis of the association between substance use
and risky sexual behavior among adolescents. 87 studies fit the inclusion criteria, containing …
and risky sexual behavior among adolescents. 87 studies fit the inclusion criteria, containing …
Cannabis in painful HIV-associated sensory neuropathy: a randomized placebo-controlled trial
DI Abrams, CA Jay, SB Shade, H Vizoso, H Reda… - Neurology, 2007 - neurology.org
Objective: To determine the effect of smoked cannabis on the neuropathic pain of HIV-
associated sensory neuropathy and an experimental pain model. Methods: Prospective …
associated sensory neuropathy and an experimental pain model. Methods: Prospective …
Human immunodeficiency virus‐associated neurocognitive disorders: mind the gap
Human immunodeficiency virus (HIV)‐associated neurocognitive disorders (HANDs) remain
among the most common disorders in people infected with HIV, even in an era when potent …
among the most common disorders in people infected with HIV, even in an era when potent …
Cervical spondylotic myelopathy
JA Tracy, JD Bartleson - The neurologist, 2010 - journals.lww.com
Background: Cervical spondylosis is part of the aging process and affects most people if
they live long enough. Degenerative changes affecting the intervertebral disks, vertebrae …
they live long enough. Degenerative changes affecting the intervertebral disks, vertebrae …
Exosomes from HIV-1-infected cells stimulate production of pro-inflammatory cytokines through trans-activating response (TAR) RNA
GC Sampey, M Saifuddin, A Schwab, R Barclay… - Journal of Biological …, 2016 - jbc.org
HIV-1 infection results in a chronic illness because long-term highly active antiretroviral
therapy can lower viral titers to an undetectable level. However, discontinuation of therapy …
therapy can lower viral titers to an undetectable level. However, discontinuation of therapy …
Mechanisms of distal axonal degeneration in peripheral neuropathies
Peripheral neuropathy is a common complication of a variety of diseases and treatments,
including diabetes, cancer chemotherapy, and infectious causes (HIV, hepatitis C, and …
including diabetes, cancer chemotherapy, and infectious causes (HIV, hepatitis C, and …