Diabetic sensorimotor peripheral neuropathy (DSPN) is a serious complication of diabetes
mellitus and is associated with increased mortality, lower-limb amputations and distressing …

To date, metformin remains the first-line oral glucose-lowering drug used for the treatment of
type 2 diabetes thanks to its well-established long-term safety and efficacy profile. Indeed …

Diabetic neuropathies are the most common chronic complications of diabetes, with an
estimated lifetime prevalence exceeding 50% in people with diabetes. Among various forms …

Metformin blocks the absorption of vitamin B12 through a mechanism that has not been
established but could be because of interference with the calcium‐dependent binding of the …

This comprehensive review establishes the role of vitamin B12 as adjunct therapy for viral
infections in the treatment and persistent symptoms of COVID-19, focusing on symptoms …

Diabetic peripheral neuropathy (DPN) is a major complication of diabetes mellitus with a
high incidence. Oxidative stress, which is a crucial pathophysiological pathway of DPN, has …

Diabetic neuropathy (DN) is a common complication of diabetes that is becoming an
increasing concern as the prevalence of diabetes rapidly rises. There are several types of …

Diabetic sensorimotor polyneuropathy (DSPN) affects around one third of people with
diabetes and accounts for considerable morbidity, increased risk of mortality, reduced …

Background and aims Metformin-treated type 2 diabetes mellitus (T2DM) patients are at
higher risk of vitamin B 12 deficiency and more severe neuropathy symptoms. There is still …

Diabetes mellitus (DM) is still one of the most common diseases worldwide, and its
prevalence is still increasing globally. According to the American and European …