The opioid epidemic, with its noticeable increase in opioid prescriptions and related misuse,
abuse and resultant deaths in the previous 12 years, is a particularly North American …

This review summarizes current evidence on the abuse and misuse of the gabapentinoids
pregabalin and gabapentin. Pharmacovigilance studies, register-based studies, surveys …

Background Drug utilization studies are essential to facilitate rational drug use in the society.
Aim In this review, we provide an overview of drug utilization measures that can be used …

Objective: In response to persistent public health concerns regarding prescription opioids,
many states and healthcare systems have implemented legislation and policies intended to …

Background Many patients use opioids chronically before surgery; it is unclear if surgery
alters the likelihood of ongoing opioid consumption in these patients. Methods We …

In France, the monitoring of drug abuse and dependence is based on the implementation of
national surveys and the collection of spontaneous reports of health professionals. Medico …

Background “Doctor shop**” typically refers to patients that seek controlled substance
prescriptions from multiple providers with the presumed intent to obtain these medications …

Aims There are increasing concerns about harms related to suboptimal antipsychotic use.
Here we describe recent population‐based trends in antipsychotic use and harms in …

In healthcare studies, the analysis of claims data is gaining an increasingly important role.
Observational studies should be reported in a manner that promotes internal and external …

Over the past decade, the LtraditionalL drug scenario has shown significant changes
because of the emergence of a range of molecules, eg the novel psychoactive substances …