Plasmodium species cause malaria by proliferating in human erythrocytes. Invasion of
immunologically privileged erythrocytes provides a relatively protective niche as well as …

Parasitic protozoa of the phylum Apicomplexa cause a range of human and animal
diseases. Their complex life cycles–often heteroxenous with sexual and asexual phases in …

The obligate intracellular lifestyle of apicomplexan parasites necessitates an invasive phase
underpinned by timely and spatially controlled secretion of apical organelles termed …

The asexual blood stages of Plasmodium falciparum cause the most lethal form of human
malaria. During growth within an infected red blood cell, parasite multiplication and …

P lasmodium spp. and T oxoplasma gondii are important human and veterinary pathogens.
These parasites possess an unusual double membrane structure located directly below the …

Mitochondria distribution in cells controls cellular physiology in health and disease. Here we
describe the mitochondrial morphology and positioning found in the different stages of the …

Malaria elimination may never succeed without the implementation of transmission-blocking
strategies. The transmission of Plasmodium spp. parasites from the human host to the …

Pathology of the most lethal form of malaria is caused by Plasmodium falciparum asexual
blood stages and initiated by merozoite invasion of erythrocytes. We present a …

Protein phosphorylation plays a fundamental role in the biology of apicomplexan parasites.
Many apicomplexan protein kinases are substantially different from their mammalian …

Malaria continues to be a significant cause of death and morbidity worldwide, and there is a
need for new antimalarial drugs with novel targets. We have focused as a potential target for …