[HTML][HTML] An updated review of lysophosphatidylcholine metabolism in human diseases

SH Law, ML Chan, GK Marathe, F Parveen… - International journal of …, 2019 - mdpi.com
Lysophosphatidylcholine (LPC) is increasingly recognized as a key marker/factor positively
associated with cardiovascular and neurodegenerative diseases. However, findings from …

[HTML][HTML] Inflammation, not cholesterol, is a cause of chronic disease

A Tsoupras, R Lordan, I Zabetakis - Nutrients, 2018 - mdpi.com
Since the Seven Countries Study, dietary cholesterol and the levels of serum cholesterol in
relation to the development of chronic diseases have been somewhat demonised. However …

Lipoprotein‐associated phospholipase A2: The story continues

F Huang, K Wang, J Shen - Medicinal research reviews, 2020 - Wiley Online Library
Inflammation is thought to play an important role in the pathogenesis of vascular diseases.
Lipoprotein‐associated phospholipase A2 (Lp‐PLA2) mediates vascular inflammation …

Emerging risk biomarkers in cardiovascular diseases and disorders

RK Upadhyay - Journal of lipids, 2015 - Wiley Online Library
Present review article highlights various cardiovascular risk prediction biomarkers by
incorporating both traditional risk factors to be used as diagnostic markers and recent …

[HTML][HTML] Cytosolic phospholipase A2: physiological function and role in disease

CC Leslie - Journal of lipid research, 2015 - Elsevier
The group IV phospholipase A 2 (PLA 2) family is comprised of six intracellular enzymes
(GIVA,-B,-C,-D,-E, and-F) commonly referred to as cytosolic PLA 2 (cPLA 2) α,-β,-γ,-δ,-ε, and …

Phospholipids of animal and marine origin: Structure, function, and anti-inflammatory properties

R Lordan, A Tsoupras, I Zabetakis - Molecules, 2017 - mdpi.com
In this review paper, the latest literature on the functional properties of phospholipids in
relation to inflammation and inflammation-related disorders has been critically appraised …

Platelet activating factor (PAF): a mediator of inflammation

JEM Upton, E Grunebaum, G Sussman, P Vadas - Biofactors, 2022 - Wiley Online Library
Platelet‐activating factor (PAF) is a phospholipid‐derived mediator with an established role
in multiple inflammatory states. PAF is synthesized and secreted by multiple cell types and is …

Forty years since the structural elucidation of platelet-activating factor (PAF): historical, current, and future research perspectives

R Lordan, A Tsoupras, I Zabetakis, CA Demopoulos - Molecules, 2019 - mdpi.com
In the late 1960s, Barbaro and Zvaifler described a substance that caused antigen induced
histamine release from rabbit platelets producing antibodies in passive cutaneous …

Platelets in the immune response: revisiting platelet-activating factor in anaphylaxis

P Gill, NL **dal, A Jagdis, P Vadas - Journal of Allergy and Clinical …, 2015 - Elsevier
Anaphylaxis is an acute, severe, life-threatening multisystem allergic reaction resulting from
the sudden systemic release of biochemical mediators and chemotactic substances …

Uterine natural killer cells: supervisors of vasculature construction in early decidua basalis

MT Rätsep, AM Felker, VR Kay, L Tolusso… - …, 2015 - rep.bioscientifica.com
Mammalian pregnancy involves tremendous de novo maternal vascular construction to
adequately support conceptus development. In early mouse decidua basalis (DB), maternal …