Purely organic room temperature phosphorescence, especially in aqueous solution, is
attracting increasing attention owing to its large Stokes shift, long lifetime, low preparation …

In this Review article, we systematically summarize the design and applications of various
kinds of long-lived emissive probes for bioimaging and biosensing via time-resolved …

When a molecule absorbs a photon of appropriate energy, a chain of photophysical events
ensues, such as internal conversion or vibrational relaxation (loss of energy in the absence …

Compared to fluorescence imaging with short-lived emissive probes, the use of
phosphorescent probes conveys the advantage of long signal persistance in time and this …

As one of the most attractive purely organic luminescent materials, thermally activated
delayed fluorescence (TADF) luminophores have drawn wide attention in the last decade …

The yeast two-hybrid system pioneered the field of in vivo protein-protein interaction
methods and undisputedly gave rise to a palette of ingenious techniques that are constantly …

Traditional screening paradigms often focus on single targets. To facilitate drug discovery in
the more complex physiological environment of a cell or organism, powerful cellular imaging …

Fluorescence lifetime imaging microscopy (FLIM) and fluorescence anisotropy imaging
microscopy (FAIM) are versatile tools for the investigation of the molecular environment of …

Epigenetic mechanisms, such as histone modifications and DNA methylation, have been
shown to play a key role in the regulation of gene transcription. Results of recent studies …

Following cell entry, the RNA genome of HIV-1 is reverse transcribed into double-stranded
DNA that ultimately integrates into the host-cell genome to establish the provirus. These …