The regulation and functions of DNA and RNA G-quadruplexes
DNA and RNA can adopt various secondary structures. Four-stranded G-quadruplex (G4)
structures form through self-recognition of guanines into stacked tetrads, and considerable …
structures form through self-recognition of guanines into stacked tetrads, and considerable …
Intracellular mRNA transport and localized translation
Fine-tuning cellular physiology in response to intracellular and environmental cues requires
precise temporal and spatial control of gene expression. High-resolution imaging …
precise temporal and spatial control of gene expression. High-resolution imaging …
BDNF-induced local protein synthesis and synaptic plasticity
G Leal, D Comprido, CB Duarte - Neuropharmacology, 2014 - Elsevier
Brain-derived neurotrophic factor (BDNF) is an important regulator of synaptic transmission
and long-term potentiation (LTP) in the hippocampus and in other brain regions, playing a …
and long-term potentiation (LTP) in the hippocampus and in other brain regions, playing a …
Alternative 3′ UTRs modify the localization, regulatory potential, stability, and plasticity of mRNAs in neuronal compartments
Neurons localize mRNAs near synapses where their translation can be regulated by
synaptic demand and activity. Differences in the 3′ UTRs of mRNAs can change their …
synaptic demand and activity. Differences in the 3′ UTRs of mRNAs can change their …
RNA G-quadruplexes in biology: principles and molecular mechanisms
Abstract G-quadruplexes (G4s) are extremely stable DNA or RNA secondary structures
formed by sequences rich in guanine. These structures are implicated in many essential …
formed by sequences rich in guanine. These structures are implicated in many essential …
Visualization and selective chemical targeting of RNA G-quadruplex structures in the cytoplasm of human cells
Following extensive evidence for the formation of four-stranded DNA G-quadruplex
structures in vitro, DNA G-quadruplexes have been observed within human cells. Although …
structures in vitro, DNA G-quadruplexes have been observed within human cells. Although …
RNA G-quadruplexes (rG4s): genomics and biological functions
Abstract G-quadruplexes (G4s) are non-classical DNA or RNA secondary structures that
have been first observed decades ago. Over the years, these four-stranded structural motifs …
have been first observed decades ago. Over the years, these four-stranded structural motifs …
5′-UTR RNA G-quadruplexes: translation regulation and targeting
RNA structures in the untranslated regions (UTRs) of mRNAs influence post-transcriptional
regulation of gene expression. Much of the knowledge in this area depends on canonical …
regulation of gene expression. Much of the knowledge in this area depends on canonical …
Properties and biological impact of RNA G-quadruplexes: from order to turmoil and back
Abstract Guanine-quadruplexes (G4s) are non-canonical four-stranded structures that can
be formed in guanine (G) rich nucleic acid sequences. A great number of G-rich sequences …
be formed in guanine (G) rich nucleic acid sequences. A great number of G-rich sequences …
G-Quadruplexes as pathogenic drivers in neurodegenerative disorders
E Wang, R Thombre, Y Shah, R Latanich… - Nucleic acids …, 2021 - academic.oup.com
Abstract G-quadruplexes (G4s), higher-order DNA and RNA secondary structures featuring
guanine-rich nucleic acid sequences with various conformations, are widely distributed in …
guanine-rich nucleic acid sequences with various conformations, are widely distributed in …