The spread and evolution of rabies virus: conquering new frontiers

CR Fisher, DG Streicker, MJ Schnell - Nature Reviews Microbiology, 2018 - nature.com
Rabies is a lethal zoonotic disease that is caused by lyssaviruses, most often rabies virus.
Despite control efforts, sporadic outbreaks in wildlife populations are largely unpredictable …

Molecular mechanism and physiological functions of clathrin-mediated endocytosis

HT McMahon, E Boucrot - Nature reviews Molecular cell biology, 2011 - nature.com
Clathrin-mediated endocytosis is the endocytic portal into cells through which cargo is
packaged into vesicles with the aid of a clathrin coat. It is fundamental to neurotransmission …

[HTML][HTML] Impact of lipid nanoparticle size on mRNA vaccine immunogenicity

KJ Hassett, J Higgins, A Woods, B Levy, Y **a… - Journal of Controlled …, 2021 - Elsevier
Lipid nanoparticles (LNP) are effective delivery vehicles for messenger RNA (mRNA) and
have shown promise for vaccine applications. Yet there are no published reports detailing …

LDL receptor and its family members serve as the cellular receptors for vesicular stomatitis virus

D Finkelshtein, A Werman, D Novick… - Proceedings of the …, 2013 - National Acad Sciences
Vesicular stomatitis virus (VSV) exhibits a remarkably robust and pantropic infectivity,
mediated by its coat protein, VSV-G. Using this property, recombinant forms of VSV and VSV …

Ebola virus entry requires the cholesterol transporter Niemann–Pick C1

JE Carette, M Raaben, AC Wong, AS Herbert… - Nature, 2011 - nature.com
Infections by the Ebola and Marburg filoviruses cause a rapidly fatal haemorrhagic fever in
humans for which no approved antivirals are available. Filovirus entry is mediated by the …

Nanoparticle elasticity regulates phagocytosis and cancer cell uptake

Y Hui, X Yi, D Wibowo, G Yang, APJ Middelberg… - Science …, 2020 - science.org
The ability of cells to sense external mechanical cues is essential for their adaptation to the
surrounding microenvironment. However, how nanoparticle mechanical properties affect cell …

Extended-resolution structured illumination imaging of endocytic and cytoskeletal dynamics

D Li, L Shao, BC Chen, X Zhang, M Zhang, B Moses… - Science, 2015 - science.org
INTRODUCTION Various methods of super-resolution (SR) fluorescence microscopy have
the potential to follow the dynamic nanoscale interactions of specific macromolecular …

Shape and orientation matter for the cellular uptake of nonspherical particles

S Dasgupta, T Auth, G Gompper - Nano letters, 2014 - ACS Publications
Recent advances in nanotechnology have made a whole zoo of particles of different shapes
available for applications, but their interaction with biological cells and their toxicity is often …

Endocytosis of viruses and bacteria

P Cossart, A Helenius - Cold Spring Harbor perspectives …, 2014 - cshperspectives.cshlp.org
Of the many pathogens that infect humans and animals, a large number use cells of the host
organism as protected sites for replication. To reach the relevant intracellular compartments …

Virus entry by endocytosis

J Mercer, M Schelhaas… - Annual review of …, 2010 - annualreviews.org
Although viruses are simple in structure and composition, their interactions with host cells
are complex. Merely to gain entry, animal viruses make use of a repertoire of cellular …