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The spread and evolution of rabies virus: conquering new frontiers
Rabies is a lethal zoonotic disease that is caused by lyssaviruses, most often rabies virus.
Despite control efforts, sporadic outbreaks in wildlife populations are largely unpredictable …
Despite control efforts, sporadic outbreaks in wildlife populations are largely unpredictable …
Molecular mechanism and physiological functions of clathrin-mediated endocytosis
HT McMahon, E Boucrot - Nature reviews Molecular cell biology, 2011 - nature.com
Clathrin-mediated endocytosis is the endocytic portal into cells through which cargo is
packaged into vesicles with the aid of a clathrin coat. It is fundamental to neurotransmission …
packaged into vesicles with the aid of a clathrin coat. It is fundamental to neurotransmission …
[HTML][HTML] Impact of lipid nanoparticle size on mRNA vaccine immunogenicity
Lipid nanoparticles (LNP) are effective delivery vehicles for messenger RNA (mRNA) and
have shown promise for vaccine applications. Yet there are no published reports detailing …
have shown promise for vaccine applications. Yet there are no published reports detailing …
LDL receptor and its family members serve as the cellular receptors for vesicular stomatitis virus
D Finkelshtein, A Werman, D Novick… - Proceedings of the …, 2013 - National Acad Sciences
Vesicular stomatitis virus (VSV) exhibits a remarkably robust and pantropic infectivity,
mediated by its coat protein, VSV-G. Using this property, recombinant forms of VSV and VSV …
mediated by its coat protein, VSV-G. Using this property, recombinant forms of VSV and VSV …
Ebola virus entry requires the cholesterol transporter Niemann–Pick C1
Infections by the Ebola and Marburg filoviruses cause a rapidly fatal haemorrhagic fever in
humans for which no approved antivirals are available. Filovirus entry is mediated by the …
humans for which no approved antivirals are available. Filovirus entry is mediated by the …
Nanoparticle elasticity regulates phagocytosis and cancer cell uptake
The ability of cells to sense external mechanical cues is essential for their adaptation to the
surrounding microenvironment. However, how nanoparticle mechanical properties affect cell …
surrounding microenvironment. However, how nanoparticle mechanical properties affect cell …
Extended-resolution structured illumination imaging of endocytic and cytoskeletal dynamics
INTRODUCTION Various methods of super-resolution (SR) fluorescence microscopy have
the potential to follow the dynamic nanoscale interactions of specific macromolecular …
the potential to follow the dynamic nanoscale interactions of specific macromolecular …
Shape and orientation matter for the cellular uptake of nonspherical particles
Recent advances in nanotechnology have made a whole zoo of particles of different shapes
available for applications, but their interaction with biological cells and their toxicity is often …
available for applications, but their interaction with biological cells and their toxicity is often …
Endocytosis of viruses and bacteria
P Cossart, A Helenius - Cold Spring Harbor perspectives …, 2014 - cshperspectives.cshlp.org
Of the many pathogens that infect humans and animals, a large number use cells of the host
organism as protected sites for replication. To reach the relevant intracellular compartments …
organism as protected sites for replication. To reach the relevant intracellular compartments …
Virus entry by endocytosis
Although viruses are simple in structure and composition, their interactions with host cells
are complex. Merely to gain entry, animal viruses make use of a repertoire of cellular …
are complex. Merely to gain entry, animal viruses make use of a repertoire of cellular …