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Liquid biopsy at the frontier of detection, prognosis and progression monitoring in colorectal cancer
H Zhou, L Zhu, J Song, G Wang, P Li, W Li, P Luo… - Molecular cancer, 2022 - Springer
Colorectal cancer (CRC) is one of the most common cancers worldwide and a leading
cause of carcinogenic death. To date, surgical resection is regarded as the gold standard by …
cause of carcinogenic death. To date, surgical resection is regarded as the gold standard by …
The secreted factors responsible for pre-metastatic niche formation: old sayings and new thoughts
Metastasis is a multistep process that requires acquisition of malignant cell phenotypes
which allow tumor cells to escape from the primary tumor site. Each of the steps during …
which allow tumor cells to escape from the primary tumor site. Each of the steps during …
Controlling escape from angiogenesis inhibitors
Selective inhibition of vascular endothelial growth factor (VEGF) increases the efficacy of
chemotherapy and has beneficial effects on multiple advanced cancers, but response is …
chemotherapy and has beneficial effects on multiple advanced cancers, but response is …
Biomarkers to predict the clinical efficacy of bevacizumab in cancer
Bevacizumab is a monoclonal antibody against vascular endothelial growth factor that has
antiangiogenic activity and improves progression-free survival in many solid malignancies …
antiangiogenic activity and improves progression-free survival in many solid malignancies …
Phase I dose-escalation study and biomarker analysis of E7080 in patients with advanced solid tumors
K Yamada, N Yamamoto, Y Yamada… - Clinical Cancer …, 2011 - aacrjournals.org
Purpose: E7080, an oral multitargeted receptor tyrosine kinase inhibitor, has antiangiogenic
and antitumor activity. This Phase I study investigated maximum tolerated dose (MTD), dose …
and antitumor activity. This Phase I study investigated maximum tolerated dose (MTD), dose …
Antiangiogenic therapies: going beyond their limits
Tumor growth requires induction of an angiogenic program, and targeting of this program
with antiangiogenic drugs shows an impact on tumor progression. However, although they …
with antiangiogenic drugs shows an impact on tumor progression. However, although they …
Growing tumor vessels: more than one way to skin a cat–implications for angiogenesis targeted cancer therapies
The establishment of a functional, integrated vascular system is instrumental for tissue
growth and homeostasis. Without blood vessels no adequate nutrition and oxygen would be …
growth and homeostasis. Without blood vessels no adequate nutrition and oxygen would be …
Liquid biopsy in colorectal cancer
S Najafi, J Majidpoor, K Mortezaee - Clinica Chimica Acta, 2024 - Elsevier
Liquid biopsy refers to a set of pathological samples retrieved from non-solid sources, such
as blood, cerebrospinal fluid, urine, and saliva through non-invasive or minimally invasive …
as blood, cerebrospinal fluid, urine, and saliva through non-invasive or minimally invasive …
Bevacizumab in the treatment of metastatic breast cancer: friend or foe?
Metastatic breast cancer (MBC) is a major cause of death among women worldwide.
Progress has been made in treating MBC with the advent of anti-estrogen therapies, potent …
Progress has been made in treating MBC with the advent of anti-estrogen therapies, potent …
Impact of exploratory biomarkers on the treatment effect of bevacizumab in metastatic breast cancer
Purpose: The addition of bevacizumab to cytotoxic chemotherapy has demonstrated a
progression-free survival (PFS) benefit in the first-line and second-line treatment of …
progression-free survival (PFS) benefit in the first-line and second-line treatment of …