Biomarkers for the progression of intermediate age-related macular degeneration

EM Lad, RP Finger, R Guymer - Ophthalmology and Therapy, 2023 - Springer
Age-related macular degeneration (AMD) is a leading cause of severe vision loss
worldwide, with a global prevalence that is predicted to substantially increase. Identifying …

OCT risk factors for development of atrophy in eyes with intermediate age-related macular degeneration

K Hirabayashi, JY Hannah, Y Wakatsuki, KM Marion… - Ophthalmology …, 2023 - Elsevier
Purpose To determine the frequency of multiple OCT biomarkers of intermediate age-related
macular degeneration (iAMD) and their relationship with the development of complete …

The impact of NF-κB on inflammatory and angiogenic processes in age-related macular degeneration

WH Almalki, SS Almujri - Experimental Eye Research, 2024 - Elsevier
Age-related macular degeneration (AMD) is a prominent cause of vision loss, characterized
by two different types, dry (atrophic) and wet (neovascular). Dry AMD is distinguished by the …

[HTML][HTML] Multimodal imaging and en face OCT detection of calcified drusen in eyes with age-related macular degeneration

J Liu, R Laiginhas, M Shen, Y Shi, J Li, O Trivizki… - Ophthalmology …, 2022 - Elsevier
Purpose En face OCT imaging was investigated as a method for the detection and
monitoring of calcified drusen in eyes with nonexudative age-related macular degeneration …

[HTML][HTML] Deep learning approaches for detecting of nascent geographic atrophy in age-related macular degeneration

H Yao, Z Wu, SS Gao, RH Guymer, V Steffen… - Ophthalmology …, 2024 - Elsevier
Purpose Nascent geographic atrophy (nGA) refers to specific features seen on OCT B-
scans, which are strongly associated with the future development of geographic atrophy …

[HTML][HTML] Spatial cluster patterns of retinal sensitivity loss in intermediate age-related macular degeneration features

M Trinh, M Kalloniatis… - … Vision Science & …, 2023 - iovs.arvojournals.org
Purpose: To examine spatial patterns of retinal sensitivity loss in the three key features of
intermediate age-related macular degeneration (iAMD). Methods: One-hundred individuals …

Non-Neovascular Age-Related Macular Degeneration Assessment: Focus on Optical Coherence Tomography Biomarkers

DA Iliescu, AC Ghita, LA Ilie, SE Voiculescu… - Diagnostics, 2024 - mdpi.com
The imagistic evaluation of non-neovascular age-related macular degeneration (AMD) is
crucial for diagnosis, monitoring progression, and guiding management of the disease. Dry …

OCT Prognostic Biomarkers for Progression to Late Age-related Macular Degeneration: A Systematic Review and Meta-analysis

M Trinh, R Cheung, A Duong, L Nivison-Smith… - Ophthalmology Retina, 2023 - Elsevier
Topic To evaluate which OCT prognostic biomarkers best predict the risk of progression from
early/intermediate to late age-related macular degeneration (AMD). Clinical Relevance …

Hyperpigmentary abnormalities in age-related macular degeneration: association with progression and impact on visual sensitivity

KL Goh, H Kumar, X Hadoux, M Jannaud… - British Journal of …, 2024 - bjo.bmj.com
Background/aims To investigate the additional prognostic value of quantifying the extent of
colour fundus photography (CFP)-defined hyperpigmentary abnormalities (HPAs) compared …

[HTML][HTML] Assessment of choriocapillaris flow prior to nascent geographic atrophy development using optical coherence tomography angiography

EC Greig, EM Moult, IN Despotovic… - … & Visual Science, 2024 - tvst.arvojournals.org
Purpose: To assess the relationship between choriocapillaris (CC) loss and the
development of nascent geographic atrophy (nGA) using optical coherence tomography …