Macrophage migration inhibitory factor (MIF) is a proinflammatory cytokine encoded within a
functionally polymorphic genetic locus. MIF was initially recognized as a cytokine generated …

Macrophage migration inhibitory (MIF) factor is an immunoregulatory cytokine whose effect
on arresting random immune cell movement was recognized several decades ago. Despite …

Neutrophils are myeloid cells that constitute 50–70% of all white blood cells in the human
circulation. Traditionally, neutrophils are viewed as the first line of defense against infections …

Purpose: microRNAs (miRNA) are small RNAs that function as post-transcriptional
regulators of gene expression. Recent evidence has shown that some miRNAs can act as …

Macrophage migration inhibitory factor (MIF) emerged in recent years as an important
inflammation mediator, playing a prominent role in the pathogenesis of various types of …

D-dopachrome tautomerase (D-DT) is a newly described cytokine and a member of the
macrophage migration inhibitory factor (MIF) protein superfamily. MIF is a broadly expressed …

Highlights•MIF acts cytokine, enzyme, endocrine hormone and chaperon-like molecule.•D-
DT, a member of the MIF family, exerts non-redundant effects from MIF.•MIF and D-DT are up …

Macrophage migration inhibitory factor (MIF) is a proinflammatory cytokine with a pleiotropic
spectrum of biological functions implicated in the pathogenesis of cancer and inflammatory …

Macrophage migration inhibitory factor (MIF) is known to be an important contributor to tumor
progression. Overexpression of MIF has been reported in different types of tumors. However …

Background MiRNAs play important roles in diverse biological processes including
tumorigenesis. However, little is known about the function and mechanism of miR-451 in …