Saffron in the treatment of depression, anxiety and other mental disorders: Current evidence and potential mechanisms of action

M Shafiee, S Arekhi, A Omranzadeh… - Journal of Affective …, 2018 - Elsevier
Background Depression and anxiety are two common mental health problems with high
economic and social costs. Currently, a number of treatments are available for patients with …

Organophosphate toxicity: updates of malathion potential toxic effects in mammals and potential treatments

AM Badr - Environmental Science and Pollution Research, 2020 - Springer
Organophosphorus insecticides toxicity is still considered a major global health problem.
Malathion is one of the most commonly used organophosphates nowadays, as being …

Zinc and central nervous system disorders

B Wang, T Fang, H Chen - Nutrients, 2023 - mdpi.com
Zinc (Zn2+) is the second most abundant necessary trace element in the human body,
exerting a critical role in many physiological processes such as cellular proliferation …

Association between organophosphorus pesticide exposure and depression risk in adults: a cross-sectional study with NHANES data

Y Wu, J Song, Q Zhang, S Yan, X Sun, W Yi, R Pan… - Environmental …, 2023 - Elsevier
Organophosphorus pesticides (OPPs) are widely used pesticides, and previous studies
showed that OPPs can increase the risk of central nervous system disorders (eg, Parkinson's …

Toxicology effects of saffron and its constituents: a review

HB Bostan, S Mehri… - Iranian journal of basic …, 2017 - pmc.ncbi.nlm.nih.gov
Saffron (Crocus sativus L.) has been considered as a medicinal plant since ancient times
and also widely used as food additive for its color, taste and odor. The pharmacological …

Crocin molecular signaling pathways at a glance: A comprehensive review

M Boozari, H Hosseinzadeh - Phytotherapy Research, 2022 - Wiley Online Library
Crocin is a hydrophilic carotenoid that is synthesized in the flowers of the Crocus genus.
Numerous in vitro and in vivo research projects have been published about the biological …

Garlic (Allium sativum) as an antidote or a protective agent against natural or chemical toxicities: A comprehensive update review

M Dorrigiv, A Zareiyan… - Phytotherapy …, 2020 - Wiley Online Library
Garlic (Allium sativum, Liliaceae) is used widely as a spice and medicinal herb not only in its
native region (Central Asia and northeastern Iran) but also all around the world. Garlic has …

[HTML][HTML] Neuroprotective potency of saffron against neuropsychiatric diseases, neurodegenerative diseases, and other brain disorders: From bench to bedside

Y Bian, C Zhao, SMY Lee - Frontiers in Pharmacology, 2020 - frontiersin.org
The increasing morbidity rates of brain disorders and conditions such as anxiety,
depression, Alzheimer's disease, and Parkinson's disease have become a severe problem …

Saffron and its derivatives, crocin, crocetin and safranal: a patent review

M Rameshrad, BM Razavi… - Expert opinion on …, 2018 - Taylor & Francis
Introduction: Saffron and its main components have traditionally been used as
pharmaceutical agents. Current experimental research projects have also exhibited their …

Milk thistle (Silybum Marianum) as an antidote or a protective agent against natural or chemical toxicities: a review

S Fanoudi, MS Alavi, G Karimi… - Drug and chemical …, 2020 - Taylor & Francis
Biological and chemical agents cause dangerous effects on human health via different
exposing ways. Recently, herbal medicine is considered as a biological and safe treatment …