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Optical imaging for screening and early cancer diagnosis in low-resource settings
Low-cost optical imaging technologies have the potential to reduce inequalities in health
care by improving the detection of precancer or early cancer and enabling more effective …
care by improving the detection of precancer or early cancer and enabling more effective …
Frontiers in artificial intelligence‐directed light‐sheet microscopy for uncovering biological phenomena and multiorgan imaging
Light‐sheet fluorescence microscopy (LSFM) introduces fast scanning of biological
phenomena with deep photon penetration and minimal phototoxicity. This advancement …
phenomena with deep photon penetration and minimal phototoxicity. This advancement …
[HTML][HTML] Building a nonclinical pathology laboratory of the future for pharmaceutical research excellence
Highlights•The nonclinical pathology laboratory (NPL) has been largely unchanged in the
last 50 years.•Digitization and automation are driving NPL operational efficiency and …
last 50 years.•Digitization and automation are driving NPL operational efficiency and …
Current landscape of advanced imaging tools for pathology diagnostics
Histopathology relies on century-old workflows of formalin fixation, paraffin embedding,
sectioning, and staining tissue specimens on glass slides. Despite being robust, this …
sectioning, and staining tissue specimens on glass slides. Despite being robust, this …
Digital labeling for 3D histology: segmenting blood vessels without a vascular contrast agent using deep learning
Recent advances in optical tissue clearing and three-dimensional (3D) fluorescence
microscopy have enabled high resolution in situ imaging of intact tissues. Using simply …
microscopy have enabled high resolution in situ imaging of intact tissues. Using simply …
Artificial intelligence in digital pathology—time for a reality check
The past decade has seen the introduction of artificial intelligence (AI)-based approaches
aimed at optimizing several workflows across many medical specialties. In clinical oncology …
aimed at optimizing several workflows across many medical specialties. In clinical oncology …
A pilot validation study comparing fluorescence-imitating brightfield imaging, a slide-free imaging method, with standard formalin-fixed, paraffin-embedded …
Context.—Digital pathology using whole slide images has been recently approved to
support primary diagnosis in clinical surgical pathology practices. Here we describe a novel …
support primary diagnosis in clinical surgical pathology practices. Here we describe a novel …
An end-to-end workflow for nondestructive 3D pathology
Recent advances in 3D pathology offer the ability to image orders of magnitude more tissue
than conventional pathology methods while also providing a volumetric context that is not …
than conventional pathology methods while also providing a volumetric context that is not …
Disrupting prostate cancer research: Challenge accepted; report from the 2023 Coffey‐Holden Prostate Cancer Academy Meeting
AK Miyahira, SC Kamran, T Jamaspishvili… - The …, 2024 - Wiley Online Library
Abstract Introduction The 2023 Coffey‐Holden Prostate Cancer Academy (CHPCA) Meeting,
themed “Disrupting Prostate Cancer Research: Challenge Accepted,” was convened at the …
themed “Disrupting Prostate Cancer Research: Challenge Accepted,” was convened at the …
Applications of digital and computational pathology and artificial intelligence in genitourinary pathology diagnostics
As machine learning (ML) solutions for genitourinary pathology image analysis are fostered
by a progressively digitized laboratory landscape, these integrable modalities usher in a …
by a progressively digitized laboratory landscape, these integrable modalities usher in a …