Engineering cell metabolism for bioproduction not only consumes building blocks and
energy molecules (eg, ATP) but also triggers energetic inefficiency inside the cell. The …

Microalgae have the potential to become microbial cell factories for lipid production. Their
ability to convert sunlight and CO 2 into valuable lipid compounds has attracted interest from …

Lignin is the most abundant phenolic polymer; thus, its decomposition by microorganisms is
fundamental to carbon cycling on earth. Lignin breakdown is initiated by depolymerization …

Reduced nicotinamide adenine dinucleotide phosphate (NADPH) is an essential electron
donor in all organisms. It provides the reducing power that drives numerous anabolic …

The field of metabolic engineering is primarily concerned with improving the biological
production of value-added chemicals, fuels and pharmaceuticals through the design …

Metabolic flux analysis (MFA) is one of the pillars of metabolic engineering. Over the past
three decades, it has been widely used to quantify intracellular metabolic fluxes in both …

Vitamin B6 is an essential nutrient with extensive applications in the medicine, food, animal
feed, and cosmetics industries. Pyridoxine (PN), the most common commercial form of …

Oleaginous microalgae have great prospects in the fields of feed, nutrition, biofuel, etc.
However, biomass and lipid productivity in microalgae remain a major economic and …

Approaches using metabolic engineering and synthetic biology to overproduce terpenoids,
such as the precursors of taxol and artemisinin, in microbial systems have achieved initial …

Producing bio-based chemicals is imperative to establish an eco-friendly circular
bioeconomy. However, the compromised titer of these biochemicals hampers their …