Gel/hydrogel‐based in situ biomaterial platforms for cancer postoperative treatment and recovery

Y Feng, Z Zhang, W Tang, Y Dai - Exploration, 2023 - Wiley Online Library
Tumor surgical resection is the major strategy for cancer treatment. Meanwhile,
perioperative treatment especially the postoperative adjuvant anticancer strategies play …

DNA functional materials assembled from branched DNA: design, synthesis, and applications

Y Dong, C Yao, Y Zhu, L Yang, D Luo… - Chemical Reviews, 2020 - ACS Publications
DNA is traditionally known as a central genetic biomolecule in living systems. From an
alternative perspective, DNA is a versatile molecular building-block for the construction of …

Stimuli‐responsive biomolecule‐based hydrogels and their applications

M Vázquez‐González, I Willner - … Chemie International Edition, 2020 - Wiley Online Library
This Review presents polysaccharides, oligosaccharides, nucleic acids, peptides, and
proteins as functional stimuli‐responsive polymer scaffolds that yield hydrogels with …

DNA hydrogel-based gene editing and drug delivery systems

F Mo, K Jiang, D Zhao, Y Wang, J Song… - Advanced Drug Delivery …, 2021 - Elsevier
Deoxyribonucleic acid (DNA) is a promising synthesizer for precisely constructing almost
arbitrary geometry in two and three dimensions. Among various DNA-based soft materials …

Programmable CRISPR-responsive smart materials

MA English, LR Soenksen, RV Gayet, H de Puig… - Science, 2019 - science.org
Stimuli-responsive materials activated by biological signals play an increasingly important
role in biotechnology applications. We exploit the programmability of CRISPR-associated …

Highly permeable DNA supramolecular hydrogel promotes neurogenesis and functional recovery after completely transected spinal cord injury

T Yuan, Y Shao, X Zhou, Q Liu, Z Zhu… - Advanced …, 2021 - Wiley Online Library
Regeneration after severe spinal cord injury cannot occur naturally in mammals.
Transplanting stem cells to the injury site is a highly promising method, but it faces many …

New developments in medical applications of hybrid hydrogels containing natural polymers

C Vasile, D Pamfil, E Stoleru, M Baican - Molecules, 2020 - mdpi.com
New trends in biomedical applications of the hybrid polymeric hydrogels, obtained by
combining natural polymers with synthetic ones, have been reviewed …

Isothermal amplification of nucleic acids

Y Zhao, F Chen, Q Li, L Wang, C Fan - Chemical reviews, 2015 - ACS Publications
Isothermal amplification of nucleic acids is a simple process that rapidly and efficiently
accumulates nucleic acid sequences at constant temperature. Since the early 1990s …

Rational design of DNA hydrogels based on molecular dynamics of polymers

Y Li, R Chen, B Zhou, Y Dong, D Liu - Advanced Materials, 2024 - Wiley Online Library
In recent years, DNA has emerged as a fascinating building material to engineer hydrogel
due to its excellent programmability, which has gained considerable attention in biomedical …

Biomedical applications of DNA‐based hydrogels

J Gačanin, CV Synatschke… - Advanced Functional …, 2020 - Wiley Online Library
Nucleic acids are gaining significant attention as versatile building blocks for the next
generation of soft materials. Due to significant advances in the chemical synthesis and …