Microbial experimental evolution uses controlled laboratory populations to study the
mechanisms of evolution. The molecular analysis of evolved populations enables empirical …

Random DNA barcodes are a versatile tool for tracking cell lineages, with applications
ranging from development to cancer to evolution. Here, we review and critically evaluate …

Somatic mutations acquired in healthy tissues as we age are major determinants of cancer
risk. Whether variants confer a fitness advantage or rise to detectable frequencies by chance …

Species interactions drive evolution while evolution shapes these interactions. The resulting
eco-evolutionary dynamics and their repeatability depend on how adaptive mutations …

A major unresolved question is how bacteria living in complex communities respond to
environmental changes. In communities, biotic interactions may either facilitate or constrain …

In rapidly adapting asexual populations, including many microbial pathogens and viruses,
numerous mutant lineages often compete for dominance within the population,,,–. These …

Since 1892, it has been widely assumed that somatic mutations are evolutionarily irrelevant
in animals because they cannot be inherited by offspring. However, some nonbilaterians …

Copy number variants (CNVs) are a pervasive source of genetic variation and evolutionary
potential, but the dynamics and diversity of CNVs within evolving populations remain …

Experimental evolution and the associated theory are underutilized in marine microbial
studies; the two fields have developed largely in isolation. Here, we review evolutionary …

The fitness effects of all possible mutations available to an organism largely shape the
dynamics of evolutionary adaptation. Yet, whether and how this adaptive landscape …