Guidelines for the use of flow cytometry and cell sorting in immunological studies

A Cossarizza, HD Chang, A Radbruch… - European journal of …, 2021 - Wiley Online Library
The third edition of Flow Cytometry Guidelines provides the key aspects to consider when
performing flow cytometry experiments and includes comprehensive sections describing …

PD-1–PD-L1 immune-checkpoint blockade in B-cell lymphomas

A Goodman, SP Patel, R Kurzrock - Nature reviews Clinical oncology, 2017 - nature.com
Cancer cells can escape T-cell-mediated cellular cytotoxicity by exploiting the inhibitory
programmed cell-death protein 1 (PD-1)/programmed cell death 1 ligand 1 (PD-L1) immune …

Guidelines for the use of flow cytometry and cell sorting in immunological studies

A Cossarizza, HD Chang, A Radbruch… - European journal of …, 2019 - Wiley Online Library
These guidelines are a consensus work of a considerable number of members of the
immunology and flow cytometry community. They provide the theory and key practical …

Targeting the bone marrow microenvironment in multiple myeloma

Y Kawano, M Moschetta, S Manier… - Immunological …, 2015 - Wiley Online Library
Multiple myeloma (MM) is characterized by clonal expansion of malignant plasma cells in
the bone marrow (BM). Despite the significant advances in treatment, MM is still a fatal …

Monoclonal gammopathy of undetermined significance (MGUS) consistently precedes multiple myeloma: a prospective study

O Landgren, RA Kyle, RM Pfeiffer… - Blood, The Journal …, 2009 - ashpublications.org
Monoclonal gammopathy of undetermined significance (MGUS) is a premalignant plasma-
cell proliferative disorder associated with a life-long risk of progression to multiple myeloma …

New therapeutic aspects of flavones: the anticancer properties of Scutellaria and its main active constituents Wogonin, Baicalein and Baicalin

M Li-Weber - Cancer treatment reviews, 2009 - Elsevier
Traditional Chinese medicines have been recently recognized as a new source of
anticancer drugs and new chemotherapy adjuvant to enhance the efficacy of chemotherapy …

Mechanism of action of immunomodulatory drugs (IMiDS) in multiple myeloma

H Quach, D Ritchie, AK Stewart, P Neeson, S Harrison… - Leukemia, 2010 - nature.com
Immunomodulatory drugs (IMiDs) are thalidomide analogues, which possess pleiotropic anti-
myeloma properties including immune-modulation, anti-angiogenic, anti-inflammatory and …

Understanding multiple myeloma pathogenesis in the bone marrow to identify new therapeutic targets

T Hideshima, C Mitsiades, G Tonon… - Nature Reviews …, 2007 - nature.com
Multiple myeloma is a plasma cell malignancy characterized by complex heterogeneous
cytogenetic abnormalities. The bone marrow microenvironment promotes multiple myeloma …

Genetic abnormalities and survival in multiple myeloma: the experience of the Intergroupe Francophone du Myelome

H Avet-Loiseau, M Attal, P Moreau, C Charbonnel… - Blood, 2007 - ashpublications.org
Acquired genomic aberrations have been shown to significantly impact survival in several
hematologic malignancies. We analyzed the prognostic value of the most frequent …

Bone marrow microenvironment in multiple myeloma progression

S Manier, A Sacco, X Leleu, IM Ghobrial… - BioMed Research …, 2012 - Wiley Online Library
Substantial advances have been made in understanding the biology of multiple myeloma
(MM) through the study of the bone marrow (BM) microenvironment. Indeed, the BM niche …