[HTML][HTML] Bioelectronic medicine: preclinical insights and clinical advances

VA Pavlov, KJ Tracey - Neuron, 2022 - cell.com
The nervous system maintains homeostasis and health. Homeostatic disruptions underlying
the pathobiology of many diseases can be controlled by bioelectronic devices targeting CNS …

[HTML][HTML] The scientific case for brain simulations

GT Einevoll, A Destexhe, M Diesmann, S Grün, V Jirsa… - Neuron, 2019 - cell.com
A key element of the European Union's Human Brain Project (HBP) and other large-scale
brain research projects is the simulation of large-scale model networks of neurons. Here, we …

Shape perception via a high-channel-count neuroprosthesis in monkey visual cortex

X Chen, F Wang, E Fernandez, PR Roelfsema - Science, 2020 - science.org
Blindness affects 40 million people across the world. A neuroprosthesis could one day
restore functional vision in the blind. We implanted a 1024-channel prosthesis in areas V1 …

[HTML][HTML] Dynamic stimulation of visual cortex produces form vision in sighted and blind humans

MS Beauchamp, D Oswalt, P Sun, BL Foster… - Cell, 2020 - cell.com
A visual cortical prosthesis (VCP) has long been proposed as a strategy for restoring useful
vision to the blind, under the assumption that visual percepts of small spots of light produced …

Virtual reality for neurorehabilitation and cognitive enhancement

DD Georgiev, I Georgieva, Z Gong, V Nanjappan… - Brain sciences, 2021 - mdpi.com
Our access to computer-generated worlds changes the way we feel, how we think, and how
we solve problems. In this review, we explore the utility of different types of virtual reality …

[HTML][HTML] Visual percepts evoked with an intracortical 96-channel microelectrode array inserted in human occipital cortex

E Fernández, A Alfaro, C Soto-Sánchez… - The Journal of clinical …, 2021 - jci.org
In this issue of the JCI, the dream of restoring useful vision to blind individuals with
neurotechnology moves one step closer to realization. Fernández et al. implanted an …

Intrinsic network architecture predicts the effects elicited by intracranial electrical stimulation of the human brain

KCR Fox, L Shi, S Baek, O Raccah, BL Foster… - Nature human …, 2020 - nature.com
Intracranial electrical stimulation (iES) of the human brain has long been known to elicit a
remarkable variety of perceptual, motor and cognitive effects, but the functional–anatomical …

Does the prefrontal cortex play an essential role in consciousness? Insights from intracranial electrical stimulation of the human brain

O Raccah, N Block, KCR Fox - Journal of Neuroscience, 2021 - jneurosci.org
A central debate in philosophy and neuroscience pertains to whether PFC activity plays an
essential role in the neural basis of consciousness. Neuroimaging and electrophysiology …

[HTML][HTML] Brain machine interfaces for vision restoration: the current state of cortical visual prosthetics

S Niketeghad, N Pouratian - Neurotherapeutics, 2019 - Elsevier
Loss of vision alters the day to day life of blind individuals and may impose a significant
burden on their family and the economy. Cortical visual prosthetics have been shown to …

Functionally distinct gamma range activity revealed by stimulus tuning in human visual cortex

E Bartoli, W Bosking, Y Chen, Y Li, SA Sheth… - Current Biology, 2019 - cell.com
Neocortical gamma activity has long been hypothesized as a mechanism for synchronizing
brain regions to support visual perception and cognition more broadly. Although early …