Migraine: disease characterisation, biomarkers, and precision medicine

M Ashina, GM Terwindt, MAM Al-Karagholi, I De Boer… - The Lancet, 2021 - thelancet.com
Migraine is a disabling neurological disorder, diagnosis of which is based on clinical criteria.
A shortcoming of these criteria is that they do not fully capture the heterogeneity of migraine …

Pathophysiology of delayed cerebral ischemia after subarachnoid hemorrhage: a review

WS Dodd, D Laurent, AS Dumont… - Journal of the …, 2021 - Am Heart Assoc
Delayed cerebral ischemia is a major predictor of poor outcomes in patients who suffer
subarachnoid hemorrhage. Treatment options are limited and often ineffective despite many …

Migraine and neuroinflammation: the inflammasome perspective

O Kursun, M Yemisci… - The journal of headache …, 2021 - Springer
Background Neuroinflammation has an important role in the pathophysiology of migraine,
which is a complex neuro-glio-vascular disorder. The main aim of this review is to highlight …

Functional vascular contributions to cognitive impairment and dementia: mechanisms and consequences of cerebral autoregulatory dysfunction, endothelial …

P Toth, S Tarantini, A Csiszar… - American Journal of …, 2017 - journals.physiology.org
Increasing evidence from epidemiological, clinical and experimental studies indicate that
age-related cerebromicrovascular dysfunction and microcirculatory damage play critical …

Real-time whole-brain imaging of hemodynamics and oxygenation at micro-vessel resolution with ultrafast wide-field photoacoustic microscopy

X Zhu, Q Huang, A DiSpirito, T Vu, Q Rong… - Light: Science & …, 2022 - nature.com
High-speed high-resolution imaging of the whole-brain hemodynamics is critically important
to facilitating neurovascular research. High imaging speed and image quality are crucial to …

Capillary K+-sensing initiates retrograde hyperpolarization to increase local cerebral blood flow

TA Longden, F Dabertrand, M Koide, AL Gonzales… - Nature …, 2017 - nature.com
Blood flow into the brain is dynamically regulated to satisfy the changing metabolic
requirements of neurons, but how this is accomplished has remained unclear. Here we …

Migraine (Primer)

MD Ferrari, PJ Goadsby, B Rami… - Nature Reviews …, 2022 - search.proquest.com
Migraine is a common, chronic, disorder that is typically characterized by recurrent disabling
attacks of headache and accompanying symptoms, including aura. The aetiology is …

The continuum of spreading depolarizations in acute cortical lesion development: examining Leao's legacy

JA Hartings, CW Shuttleworth… - Journal of Cerebral …, 2017 - journals.sagepub.com
A modern understanding of how cerebral cortical lesions develop after acute brain injury is
based on Aristides Leão's historic discoveries of spreading depression and asphyxial/anoxic …

[HTML][HTML] Neural stem cell grafts form extensive synaptic networks that integrate with host circuits after spinal cord injury

S Ceto, KJ Sekiguchi, Y Takashima, A Nimmerjahn… - Cell stem cell, 2020 - cell.com
Neural stem/progenitor cell (NSPC) grafts can integrate into sites of spinal cord injury (SCI)
and generate neuronal relays across lesions that can provide functional benefit. To …

Migraine and risk of stroke

LR Øie, T Kurth, S Gulati, DW Dodick - Journal of Neurology …, 2020 - jnnp.bmj.com
Migraine and stroke are two common and heterogeneous neurovascular disorders
responsible for a significant burden for those affected and a great economic cost for the …