Modified muscle use or injury can produce a stereotypic inflammatory response in which
neutrophils rapidly invade, followed by macrophages. This inflammatory response coincides …

Recent discoveries reveal complex interactions between skeletal muscle and the immune
system that regulate muscle regeneration. In this review, we evaluate evidence that …

Muscle injuries are one of the most common traumas occurring in sports. Despite their
clinical importance, few clinical studies exist on the treatment of these traumas. Thus, the …

Regulated expression of the H19 long noncoding RNA gene has been well characterized as
a paradigm for genomic imprinting, but the H19 RNA's biological function remains largely …

Skeletal muscle satellite cells are adult stem cells responsible for postnatal skeletal muscle
growth and regeneration. Paired-box transcription factor Pax7 plays a central role in satellite …

Peroxisome proliferator-activated receptor γ co-activator 1α (PGC-1α) promotes
mitochondrial biogenesis and slow fiber formation in skeletal muscle. We hypothesized that …

Skeletal muscle continuously adapts to changes in its mechanical environment through
modifications in gene expression and protein stability that affect its physiological function …

Somatic stem cell populations participate in the development and regeneration of their host
tissues. Skeletal muscle is capable of complete regeneration due to stem cells that reside in …

Skeletal muscle injuries occur frequently in daily life and exercise. Understanding the
mechanisms of regeneration is critical for accelerating the repair and regeneration of …

Skeletal muscle arises from the fusion of precursor myoblasts into multinucleated myofibres,.
Although conserved transcription factors and signalling proteins involved in myogenesis …