Introduction: Chemotherapy of malaria has become a rapidly changing field. Less than two
decades ago, treatment regimens were increasingly bound to fail due to emerging drug …

Background Artemisinin combination therapy (ACT) is recommended as first-line treatment
for uncomplicated Plasmodium falciparum malaria, whereas chloroquine is still commonly …

The fight against malaria is a continuum as the epidemic is not abating. For proper
deployment of tools in the fight against malaria, an assessment of the situation is necessary …

Malaria is one of the most important infectious tropical diseases. Rapid and accurate
diagnostics are the basis of therapeutic care for most febrile patients in field clinics and …

Ubiquitin-dependent protein degradation within malarial parasites is a burgeoning field of
interest due to several encouraging reports of proteasome inhibitors that were able to confer …

Background Two platyhelminths of biomedical and commercial significance are
Schistosoma mansoni (blood fluke) and Fasciola hepatica (liver fluke). These related …

The tolerability, safety, and disposition of dihydroartemisinin (DHA) and piperaquine (PQ)
were assessed in 32 pregnant (second/third trimester) and 33 nonpregnant Papua New …

Protozoan parasites interact with a wide variety of organisms ranging from bacteria to
humans, representing one of the most common causes of parasitic diseases and an …

Background Recent studies alluded to the alarming scale of poor anti-malarial drug quality
in malaria-endemic countries, but also illustrated the major geographical gaps in data on …

Neglected tropical diseases (NTDs) constitute a group of diseases that generally develop in
tropical or subtropical climatic conditions and are related to poverty. Within the spectrum of …