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Mixed selectivity: Cellular computations for complexity
The property of mixed selectivity has been discussed at a computational level and offers a
strategy to maximize computational power by adding versatility to the functional role of each …
strategy to maximize computational power by adding versatility to the functional role of each …
Dopamine and cognitive control in prefrontal cortex
Cognitive control, the ability to orchestrate behavior in accord with our goals, depends on
the prefrontal cortex. These cognitive functions are heavily influenced by the …
the prefrontal cortex. These cognitive functions are heavily influenced by the …
Brain network dynamics during working memory are modulated by dopamine and diminished in schizophrenia
Dynamical brain state transitions are critical for flexible working memory but the network
mechanisms are incompletely understood. Here, we show that working memory …
mechanisms are incompletely understood. Here, we show that working memory …
Macroscopic gradients of synaptic excitation and inhibition in the neocortex
XJ Wang - Nature reviews neuroscience, 2020 - nature.com
With advances in connectomics, transcriptome and neurophysiological technologies, the
neuroscience of brain-wide neural circuits is poised to take off. A major challenge is to …
neuroscience of brain-wide neural circuits is poised to take off. A major challenge is to …
Theory of the multiregional neocortex: large-scale neural dynamics and distributed cognition
XJ Wang - Annual review of neuroscience, 2022 - annualreviews.org
The neocortex is a complex neurobiological system with many interacting regions. How
these regions work together to subserve flexible behavior and cognition has become …
these regions work together to subserve flexible behavior and cognition has become …
Deep neural networks in psychiatry
Abstract Machine and deep learning methods, today's core of artificial intelligence, have
been applied with increasing success and impact in many commercial and research …
been applied with increasing success and impact in many commercial and research …
Functional connectivity dynamically evolves on multiple time-scales over a static structural connectome: Models and mechanisms
Over the last decade, we have observed a revolution in brain structural and functional
Connectomics. On one hand, we have an ever-more detailed characterization of the brain's …
Connectomics. On one hand, we have an ever-more detailed characterization of the brain's …
Orbitofrontal cortex: a neural circuit for economic decisions
Economic choice behavior entails the computation and comparison of subjective values. A
central contribution of neuroeconomics has been to show that subjective values are …
central contribution of neuroeconomics has been to show that subjective values are …
The role of default network deactivation in cognition and disease
A considerable body of evidence has accumulated over recent years on the functions of the
default-mode network (DMN)–a set of brain regions whose activity is high when the mind is …
default-mode network (DMN)–a set of brain regions whose activity is high when the mind is …
Resting-state functional connectivity emerges from structurally and dynamically shaped slow linear fluctuations
Brain fluctuations at rest are not random but are structured in spatial patterns of correlated
activity across different brain areas. The question of how resting-state functional connectivity …
activity across different brain areas. The question of how resting-state functional connectivity …