Mixed selectivity: Cellular computations for complexity

KM Tye, EK Miller, FH Taschbach, MK Benna, M Rigotti… - Neuron, 2024 - cell.com
The property of mixed selectivity has been discussed at a computational level and offers a
strategy to maximize computational power by adding versatility to the functional role of each …

Dopamine and cognitive control in prefrontal cortex

T Ott, A Nieder - Trends in cognitive sciences, 2019 - cell.com
Cognitive control, the ability to orchestrate behavior in accord with our goals, depends on
the prefrontal cortex. These cognitive functions are heavily influenced by the …

Brain network dynamics during working memory are modulated by dopamine and diminished in schizophrenia

U Braun, A Harneit, G Pergola, T Menara… - Nature …, 2021 - nature.com
Dynamical brain state transitions are critical for flexible working memory but the network
mechanisms are incompletely understood. Here, we show that working memory …

Macroscopic gradients of synaptic excitation and inhibition in the neocortex

XJ Wang - Nature reviews neuroscience, 2020 - nature.com
With advances in connectomics, transcriptome and neurophysiological technologies, the
neuroscience of brain-wide neural circuits is poised to take off. A major challenge is to …

Theory of the multiregional neocortex: large-scale neural dynamics and distributed cognition

XJ Wang - Annual review of neuroscience, 2022 - annualreviews.org
The neocortex is a complex neurobiological system with many interacting regions. How
these regions work together to subserve flexible behavior and cognition has become …

Deep neural networks in psychiatry

D Durstewitz, G Koppe, A Meyer-Lindenberg - Molecular psychiatry, 2019 - nature.com
Abstract Machine and deep learning methods, today's core of artificial intelligence, have
been applied with increasing success and impact in many commercial and research …

Functional connectivity dynamically evolves on multiple time-scales over a static structural connectome: Models and mechanisms

J Cabral, ML Kringelbach, G Deco - NeuroImage, 2017 - Elsevier
Over the last decade, we have observed a revolution in brain structural and functional
Connectomics. On one hand, we have an ever-more detailed characterization of the brain's …

Orbitofrontal cortex: a neural circuit for economic decisions

C Padoa-Schioppa, KE Conen - Neuron, 2017 - cell.com
Economic choice behavior entails the computation and comparison of subjective values. A
central contribution of neuroeconomics has been to show that subjective values are …

The role of default network deactivation in cognition and disease

A Anticevic, MW Cole, JD Murray, PR Corlett… - Trends in cognitive …, 2012 - cell.com
A considerable body of evidence has accumulated over recent years on the functions of the
default-mode network (DMN)–a set of brain regions whose activity is high when the mind is …

Resting-state functional connectivity emerges from structurally and dynamically shaped slow linear fluctuations

G Deco, A Ponce-Alvarez, D Mantini… - Journal of …, 2013 - jneurosci.org
Brain fluctuations at rest are not random but are structured in spatial patterns of correlated
activity across different brain areas. The question of how resting-state functional connectivity …