Pathogenesis of systemic lupus erythematosus: risks, mechanisms and therapeutic targets

MK Crow - Annals of the rheumatic diseases, 2023‏ - Elsevier
Research elucidating the pathogenesis of systemic lupus erythematosus (SLE) has defined
two critical families of mediators, type I interferon (IFN-I) and autoantibodies targeting nucleic …

[PDF][PDF] An overview of systemic lupus erythematosus (SLE) pathogenesis, classification, and management

MA Ameer, H Chaudhry, J Mushtaq, OS Khan, M Babar… - Cureus, 2022‏ - cureus.com
Systemic lupus erythematosus (SLE) is a complex autoimmune disease with multisystem
involvement. It is multifactorial and involves epigenetic, genetic, ecological, and …

CD19 CAR T-cell therapy in autoimmune disease—a case series with follow-up

F Müller, J Taubmann, L Bucci, A Wilhelm… - … England Journal of …, 2024‏ - Mass Medical Soc
Background Treatment for autoimmune diseases such as systemic lupus erythematosus
(SLE), idiopathic inflammatory myositis, and systemic sclerosis often involves long-term …

The 2023 ACR/EULAR antiphospholipid syndrome classification criteria

M Barbhaiya, S Zuily, R Naden, A Hendry… - Arthritis & …, 2023‏ - Wiley Online Library
Objective To develop new antiphospholipid syndrome (APS) classification criteria with high
specificity for use in observational studies and trials, jointly supported by the American …

EULAR recommendations for the management of systemic lupus erythematosus: 2023 update

A Fanouriakis, M Kostopoulou, J Andersen… - Annals of the rheumatic …, 2024‏ - Elsevier
Objectives To update the EULAR recommendations for the management of systemic lupus
erythematosus (SLE) based on emerging new evidence. Methods An international Task …

Global epidemiology of systemic lupus erythematosus: a comprehensive systematic analysis and modelling study

J Tian, D Zhang, X Yao, Y Huang, Q Lu - Annals of the rheumatic …, 2023‏ - ard.bmj.com
Objectives To quantify global, regional and country-specific estimates of epidemiology of
systemic lupus erythematosus (SLE). Methods Four databases were systematically …

Single-cell RNA-seq reveals cell type–specific molecular and genetic associations to lupus

RK Perez, MG Gordon, M Subramaniam, MC Kim… - Science, 2022‏ - science.org
Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease. Knowledge
of circulating immune cell types and states associated with SLE remains incomplete. We …

Systemic lupus erythematosus: a review

CH Siegel, LR Sammaritano - Jama, 2024‏ - jamanetwork.com
Importance Systemic lupus erythematosus (SLE) is a chronic autoimmune disease
characterized by inflammation and immune-mediated injury to multiple organ systems …

Anti-CD19 CAR T cell therapy for refractory systemic lupus erythematosus

A Mackensen, F Müller, D Mougiakakos, S Böltz… - Nature medicine, 2022‏ - nature.com
Systemic lupus erythematosus (SLE) is a life-threatening autoimmune disease characterized
by adaptive immune system activation, formation of double-stranded DNA autoantibodies …

Global epidemiology of systemic lupus erythematosus

MRW Barber, C Drenkard, T Falasinnu, A Hoi… - Nature Reviews …, 2021‏ - nature.com
Systemic lupus erythematosus (SLE) is an autoimmune disease with protean manifestations
that predominantly affects young women. Certain ethnic groups are more vulnerable than …