During aging the immune system (IS) undergoes remarkable changes that collectively are
known as immunosenescence. It is a multifactorial and dynamic phenomenon that affects …

The inflammaging concept was introduced in 2000 by Prof. Franceschi. This was an
evolutionary or rather a revolutionary conceptualization of the immune changes in response …

“Frailty” is a term used to refer to a state characterized by enhanced vulnerability to, and
impaired recovery from, stressors compared with a nonfrail state, which is increasingly …

About a year ago, members of the editorial board of Biogerontology were requested to
respond to a query by the editor-in-chief of the journal as to what one question within their …

Compositional changes of cell types are main drivers of biological processes. Their
detection through single-cell experiments is difficult due to the compositionality of the data …

Ageing of the global population has become a public health concern with an important socio-
economic dimension. Ageing is characterized by an increase in the concentration of …

Inflamm‐aging is a challenging and promising new branch of aging‐related research fields
that includes areas such as immunosenescence. Increasing evidence indicates that inflamm …

The aging process involves changes in physiological, pathological, social, and
psychological conditions of a person. Nutrition is an important element of health among the …

In this paper we extend the “network theory of aging,” and we argue that a global reduction
in the capacity to cope with a variety of stressors and a concomitant progressive increase in …

The gut microbiota (GM) is a complex, evolutionarily molded ecological system, which
contributes to a variety of physiological functions. The GM is highly dynamic, being sensitive …