Mechanical signalling affects multiple biological processes during development and in adult
organisms, including cell fate transitions, cell migration, morphogenesis and immune …

Tissue and organ development during embryogenesis relies on the collective and
coordinated action of many cells. Recent studies have revealed that tissue material …

Hydrogels hold promise in agriculture as reservoirs of water in dry soil, potentially alleviating
the burden of irrigation. However, confinement in soil can markedly reduce the ability of …

Living tissues are active, multifunctional materials capable of generating, sensing,
withstanding and responding to mechanical stress. These capabilities enable tissues to …

Stiffness and forces are two fundamental quantities essential to living cells and tissues.
However, it has been a challenge to quantify both 3D traction forces and stiffness (or …

Force exertion is an integral part of cellular behavior. Traction force microscopy (TFM) has
been instrumental for studying such forces, providing spatial force measurements at …

In cancer, solid stresses impede the delivery of therapeutics to tumours and the trafficking
and tumour infiltration of immune cells. Understanding such consequences and the origin of …

Active biomaterials offer novel approaches to study mechanotransduction in mammalian
cells. These material systems probe cellular responses by dynamically modulating their …

Human organotypic and organoid cultures provide increasingly life‐like models of
tissue/organ development and disease, enable more realistic drug screening, and may …

Phagocytosis requires rapid actin reorganization and spatially controlled force generation to
ingest targets ranging from pathogens to apoptotic cells. How actomyosin activity directs …