Chronic myeloid leukaemia (CML) is a myeloproliferative disorder arising in the
haemopoietic stem cell (HSC) compartment. This disease is characterised by a reciprocal t …

Simple Summary In the last two decades, the therapeutic landscape of several tumors have
changed profoundly with the introduction of drugs against proteins encoded by oncogenes …

Chronic myeloid leukaemia (CML) is a myeloproliferative disorder of the haemopoietic stem
cell. Understanding the molecular biology of CML began with the discovery of the …

Chronic myeloid leukaemia originates in a single haematopoietic stem cell that acquires a
fusion gene resulting from a reciprocal translocation of genetic material involving one …

In human chronic myeloid leukaemia, the tyrosine-kinase oncogene BCR/ABL1 is one of the
key factors that determine most of its characteristics. Myeloproliferative diseases such as …

The constitutively active tyrosine-kinase BCR/ABL1 oncogene plays a key role in human
chronic myeloid leukemia development and disease maintenance, and determines most of …

Me pide el Dr. José María Sillero que prologue uno de sus, como siempre, interesantes,
completísimos y actualísimos trabajos, que trata sobre Desórdenes mieloproliferativos. Que …