Biomolecular coronas provide the biological identity of nanosized materials
Fundamentally, all interactions between the nanoparticle corona complex and the biological
machinery are mediated by physical forces common to all molecular systems. The …
machinery are mediated by physical forces common to all molecular systems. The …
Environmental dimensions of the protein corona
The adsorption of biomolecules to the surface of engineered nanomaterials, known as
corona formation, defines their biological identity by altering their surface properties and …
corona formation, defines their biological identity by altering their surface properties and …
Rapid formation of plasma protein corona critically affects nanoparticle pathophysiology
S Tenzer, D Docter, J Kuharev… - Nano-enabled …, 2020 - taylorfrancis.com
Rapid corona formation is found to affect haemolysis, thrombocyte activation, nanoparticle
uptake and endothelial cell death at an early exposure time. Collectively, depending on the …
uptake and endothelial cell death at an early exposure time. Collectively, depending on the …
[HTML][HTML] Key roles of adjuvants in modern vaccines
SG Reed, MT Orr, CB Fox - Nature medicine, 2013 - nature.com
Vaccines containing novel adjuvant formulations are increasingly reaching advanced
development and licensing stages, providing new tools to fill previously unmet clinical …
development and licensing stages, providing new tools to fill previously unmet clinical …
[HTML][HTML] Engineering nanoparticle toolkits for mRNA delivery
The concept of using mRNA to produce its own medicine in situ in the body makes it an ideal
drug candidate, holding great potential to revolutionize the way we approach medicine. The …
drug candidate, holding great potential to revolutionize the way we approach medicine. The …
The impact of nanoparticle protein corona on cytotoxicity, immunotoxicity and target drug delivery
In a perfect sequence of events, nanoparticles (NPs) are injected into the bloodstream
where they circulate until they reach the target tissue. The ligand on the NP surface …
where they circulate until they reach the target tissue. The ligand on the NP surface …
Protein corona fingerprinting predicts the cellular interaction of gold and silver nanoparticles
Using quantitative models to predict the biological interactions of nanoparticles will
accelerate the translation of nanotechnology. Here, we characterized the serum protein …
accelerate the translation of nanotechnology. Here, we characterized the serum protein …
The nanoparticle biomolecule corona: lessons learned–challenge accepted?
D Docter, D Westmeier, M Markiewicz… - Chemical Society …, 2015 - pubs.rsc.org
Besides the wide use of engineered nanomaterials (NMs) in technical products, their
applications are not only increasing in biotechnology and biomedicine, but also in the …
applications are not only increasing in biotechnology and biomedicine, but also in the …
Micro-and nanoplastics–current state of knowledge with the focus on oral uptake and toxicity
MB Paul, V Stock, J Cara-Carmona, E Lisicki… - Nanoscale …, 2020 - pubs.rsc.org
The production and use of plastics has constantly increased over the last 30 years. Over one
third of the plastics is used in disposables, which are discarded within three years of their …
third of the plastics is used in disposables, which are discarded within three years of their …
Altered behavior, physiology, and metabolism in fish exposed to polystyrene nanoparticles
The use of nanoparticles in consumer products, for example, cosmetics, sunscreens, and
electrical devices, has increased tremendously over the past decade despite insufficient …
electrical devices, has increased tremendously over the past decade despite insufficient …