The recent identification of cannabinoid receptors and their endogenous lipid ligands has
triggered an exponential growth of studies exploring the endocannabinoid system and its …

During the last few years, the endocannabinoid system has emerged as a highly relevant
topic in the scientific community. Many different regulatory actions have been attributed to …

The Cannabis sativa herb contains over 100 phytocannabinoid (pCB) compounds and has
been used for thousands of years for both recreational and medicinal purposes. In the past …

Endocannabinoids are implicated in appetite and body weight regulation. In rodents,
anandamide stimulates eating by actions at central CB1 receptors, and hypothalamic …

Marijuana and its major psychotropic component, Δ9-tetrahydrocannabinol, stimulate
appetite and increase body weight in wasting syndromes, suggesting that the CB1 …

OBJECTIVE: There is growing evidence for an implication of the CB1 receptor subtype of the
endocannabinoid system in the regulation of eating and fat deposition. To further define the …

Because the CB1 receptor antagonist SR141716 was previously reported to modulate food
intake in rodents, we studied its efficacy in reducing obesity in a diet-induced obesity (DIO) …

Cannabinoid drugs such as Δ 9-THC are euphoric and rewarding, and also stimulate food
intake in humans and animals. Little is known about how naturally occurring endogenous …

Endocannabinoids and ghrelin are potent appetite stimulators and are known to interact at a
hypothalamic level. However, both also have important peripheral actions, including …

The endocannabinoid system (eCB) is implicated in the mediation of both reward and
reinforcement. This is evidenced by the ability of exogenous cannabinoid drugs to produce …