Oxidative stress: an essential factor in the pathogenesis of gastrointestinal mucosal diseases

A Bhattacharyya, R Chattopadhyay… - Physiological …, 2014‏ - journals.physiology.org
Reactive oxygen species (ROS) are generated as by-products of normal cellular metabolic
activities. Superoxide dismutase, glutathione peroxidase, and catalase are the enzymes …

[HTML][HTML] Mitochondria and reactive oxygen species

AJ Kowaltowski, NC de Souza-Pinto… - Free Radical Biology …, 2009‏ - Elsevier
Mitochondria are a quantitatively relevant source of reactive oxygen species (ROS) in the
majority of cell types. Here we review the sources and metabolism of ROS in this organelle …

Mitochondria as a source of reactive oxygen and nitrogen species: from molecular mechanisms to human health

TR Figueira, MH Barros, AA Camargo… - Antioxidants & redox …, 2013‏ - liebertpub.com
Mitochondrially generated reactive oxygen species are involved in a myriad of signaling and
damaging pathways in different tissues. In addition, mitochondria are an important target of …

Redox control and oxidative stress in yeast cells

E Herrero, J Ros, G Bellí, E Cabiscol - Biochimica et Biophysica Acta (BBA) …, 2008‏ - Elsevier
Protein structure and function can be altered by reactive oxygen species produced either by
cell metabolism or by external oxidants. Although catalases, superoxide dismutases and …

Mitochondrial dysfunction resulting from loss of cytochrome c impairs cellular oxygen sensing and hypoxic HIF-α activation

KD Mansfield, RD Guzy, Y Pan, RM Young, TP Cash… - Cell metabolism, 2005‏ - cell.com
While cellular responses to low oxygen (O 2) or hypoxia have been studied extensively, the
precise identity of mammalian cellular O 2 sensors remains controversial. Using murine …

[HTML][HTML] Reactive oxygen species and yeast apoptosis

GG Perrone, SX Tan, IW Dawes - … et Biophysica Acta (BBA)-Molecular Cell …, 2008‏ - Elsevier
Apoptosis is associated in many cases with the generation of reactive oxygen species (ROS)
in cells across a wide range of organisms including lower eukaryotes such as the yeast …

Estrogen increases mitochondrial efficiency and reduces oxidative stress in cerebral blood vessels

C Stirone, SP Duckles, DN Krause, V Procaccio - Molecular pharmacology, 2005‏ - Elsevier
We report here that estrogen (E 2) modulates mitochondrial function in the vasculature.
Mitochondrial dysfunction is implicated in the etiology of vascular disease; thus …

[HTML][HTML] Higher respiratory activity decreases mitochondrial reactive oxygen release and increases life span in Saccharomyces cerevisiae

MH Barros, B Bandy, EB Tahara… - Journal of Biological …, 2004‏ - Elsevier
Increased replicative longevity in Saccharomyces cerevisiae because of calorie restriction
has been linked to enhanced mitochondrial respiratory activity. Here we have further …

The protective effects of melatonin on oxidative damage and the immune system of the Chinese mitten crab (Eriocheir sinensis) exposed to deltamethrin

C Zhang, Q Zhang, Y Pang, X Song, N Zhou… - Science of the Total …, 2019‏ - Elsevier
Deltamethrin (Del), an important broad-spectrum insecticide, is widely used in agricultural
activities. However, Del is an effective reactive oxygen species (ROS) inducer that induces …

Real-Time Observation of Conformational Changes and translocation of endogenous cytochrome c within Intact Mitochondria

J Zhan, D Zeng, X **ao, Z Fang, T Huang… - Journal of the …, 2024‏ - ACS Publications
Cytochrome c (cyt c) is a multifunctional protein with varying conformations. However, the
conformation of cyt c in its native environment, mitochondria, is still unclear. Here, we …