Unraveling the mechanistic effects of electric field stimulation towards directing stem cell fate and function: A tissue engineering perspective

G Thrivikraman, SK Boda, B Basu - Biomaterials, 2018 - Elsevier
Electric field (EF) stimulation can play a vital role in eliciting appropriate stem cell response.
Such an approach is recently being established to guide stem cell differentiation through …

Emerging roles of the membrane potential: action beyond the action potential

L Abdul Kadir, M Stacey, R Barrett-Jolley - Frontiers in physiology, 2018 - frontiersin.org
Whilst the phenomenon of an electrical resting membrane potential (RMP) is a central tenet
of biology, it is nearly always discussed as a phenomenon that facilitates the propagation of …

The matrix environmental and cell mechanical properties regulate cell migration and contribute to the invasive phenotype of cancer cells

CT Mierke - Reports on Progress in Physics, 2019 - iopscience.iop.org
The minimal structural unit of a solid tumor is a single cell or a cellular compartment such as
the nucleus. A closer look inside the cells reveals that there are functional compartments or …

Membrane potential and cancer progression

M Yang, WJ Brackenbury - Frontiers in physiology, 2013 - frontiersin.org
Membrane potential (Vm), the voltage across the plasma membrane, arises because of the
presence of different ion channels/transporters with specific ion selectivity and permeability …

Controlling cell behavior electrically: current views and future potential

CD McCaig, AM Rajnicek, B Song… - Physiological …, 2005 - journals.physiology.org
Direct-current (DC) electric fields are present in all develo** and regenerating animal
tissues, yet their existence and potential impact on tissue repair and development are …

Role of membrane potential in the regulation of cell proliferation and differentiation

S Sundelacruz, M Levin, DL Kaplan - Stem cell reviews and reports, 2009 - Springer
Biophysical signaling, an integral regulator of long-term cell behavior in both excitable and
non-excitable cell types, offers enormous potential for modulation of important cell functions …

Tumour-on-a-chip: microfluidic models of tumour morphology, growth and microenvironment

HF Tsai, A Trubelja, AQ Shen… - Journal of The Royal …, 2017 - royalsocietypublishing.org
Cancer remains one of the leading causes of death, albeit enormous efforts to cure the
disease. To overcome the major challenges in cancer therapy, we need to have a better …

Voltage-gated sodium channel expression and potentiation of human breast cancer metastasis

SP Fraser, JKJ Diss, AM Chioni, ME Mycielska… - Clinical cancer …, 2005 - AACR
Purpose: Ion channel activity is involved in several basic cellular behaviors that are integral
to metastasis (eg, proliferation, motility, secretion, and invasion), although their contribution …

Cellular mechanisms of direct-current electric field effects: galvanotaxis and metastatic disease

ME Mycielska, MBA Djamgoz - Journal of cell science, 2004 - journals.biologists.com
Endogenous direct-current electric fields (dcEFs) occur in vivo in the form of epithelial
transcellular potentials or neuronal field potentials, and a variety of cells respond to dcEFs in …

Review on cell mechanics: experimental and modeling approaches

ML Rodriguez, PJ McGarry… - Applied …, 2013 - asmedigitalcollection.asme.org
The interplay between the mechanical properties of cells and the forces that they produce
internally or that are externally applied to them play an important role in maintaining the …