Exploring the out of sight antigens of SARS-CoV-2 to design a candidate multi-epitope vaccine by utilizing immunoinformatics approaches

A Safavi, A Kefayat, E Mahdevar, A Abiri… - Vaccine, 2020 - Elsevier
SARS-CoV-2 causes a severe respiratory disease called COVID-19. Currently, global health
is facing its devastating outbreak. However, there is no vaccine available against this virus …

Immunoinformatics prediction of overlap** CD8+ T-cell, IFN-γ and IL-4 inducer CD4+ T-cell and linear B-cell epitopes based vaccines against COVID-19 (SARS …

AJ Fatoba, L Maharaj, VT Adeleke, M Okpeku… - Vaccine, 2021 - Elsevier
At the beginning of the year 2020, the world was struck with a global pandemic virus referred
to as SARS-CoV-2 (COVID-19) which has left hundreds of thousands of people dead. To …

The correlation between subolesin-reactive epitopes and vaccine efficacy

M Contreras, PD Kasaija, F Kabi, S Mugerwa… - Vaccines, 2022 - mdpi.com
Vaccination is an environmentally-friendly alternative for tick control. The tick antigen
Subolesin (SUB) has shown protection in vaccines for the control of multiple tick species in …

Immunoinformatics studies and design of a potential multi-epitope peptide vaccine to combat the fatal visceral leishmaniasis

OS Onile, F Musaigwa, N Ayawei, V Omoboyede… - Vaccines, 2022 - mdpi.com
Leishmaniasis is a neglected tropical disease caused by parasitic intracellular protozoa of
the genus Leishmania. The visceral form of this disease caused by Leishmania donovani …

Designing an epitope vaccine against Dermatophagoides pteronyssinus: An in silico study

A Adji, NJ Niode, VV Memah, J Posangi… - Acta Tropica, 2021 - Elsevier
The house dust mite, Dermatophagoides pteronyssinus, is a major source of the inhaled
allergen Der p 1, which causes immunoglobulin E (IgE)-mediated hypersensitivity reactions …

In silico design of a novel hybrid epitope-based antigen harboring highly exposed immunogenic peptides of BamA, OmpA, and Omp34 against Acinetobacter …

A Hessami, Z Mogharari, F Rahim, B Khalesi… - International …, 2024 - Elsevier
Acinetobacter baumannii, is among the highest priority bacteria according to the WHO
categorization which necessitate the exploration of alternative strategies such as …

Novel insights into the somatic proteome of Strongyloides stercoralis infective third-stage larvae

K Dishnica, C Piubelli, M Manfredi, RT Kondaveeti… - Parasites & …, 2023 - Springer
Background Strongyloidiasis is a neglected tropical disease affecting an estimated 600
million people, particularly in resource-limited settings. The infection can persist lifelong due …

NetBCE: an interpretable deep neural network for accurate prediction of linear B-cell epitopes

H Xu, Z Zhao - Genomics, Proteomics and Bioinformatics, 2022 - academic.oup.com
Identification of B-cell epitopes (BCEs) plays an essential role in the development of peptide
vaccines and immuno-diagnostic reagents, as well as antibody design and production. In …

Exploring the genetic diversity pattern of PvEBP/DBP2: A promising candidate for an effective Plasmodium vivax vaccine

LJ Hernández-Zambrano, H Alfonso-González… - Acta Tropica, 2024 - Elsevier
Malaria remains a public health challenge. Since many control strategies have proven
ineffective in eradicating this disease, new strategies are required, among which the design …

[PDF][PDF] Bioinformatics characterization of Plasmodium knowlesi apical membrane antigen 1 (PkAMA1) for multi-epitope vaccine design.

A Azazi, FN Haron, KH Chua, YAL Lim, PC Lee… - 2021 - academia.edu
Malaria caused by Plasmodium knowlesi species has become a public health concern,
especially in Malaysia. Plasmodium knowlesi parasite which originates from the macaque …