The therapeutic journey of benzimidazoles: A review
Presence of benzimidazole nucleus in numerous categories of therapeutic agents such as
antimicrobials, antivirals, antiparasites, anticancer, anti-inflammatory, antioxidants, proton …
antimicrobials, antivirals, antiparasites, anticancer, anti-inflammatory, antioxidants, proton …
Benzimidazole: an emerging scaffold for analgesic and anti-inflammatory agents
M Gaba, S Singh, C Mohan - European journal of medicinal chemistry, 2014 - Elsevier
Within the vast range of heterocycles, benzimidazole and its derivatives are found to be
trendy structures employed for discovery of drugs in the field of pharmaceutical and …
trendy structures employed for discovery of drugs in the field of pharmaceutical and …
Structure–activity relationship analysis of benzimidazoles as emerging anti-inflammatory agents: An overview
A significant number of the anti-inflammatory drugs currently in use are becoming obsolete.
These are exceptionally hazardous for long-term use because of their possible unfavourable …
These are exceptionally hazardous for long-term use because of their possible unfavourable …
[HTML][HTML] Greener organic synthetic methods: Sonochemistry and heterogeneous catalysis promoted multicomponent reactions
Ultrasound is an essential technique to improve organic synthesis from the point of view of
green chemistry, as it can promote better yields and selectivities, in addition to shorter …
green chemistry, as it can promote better yields and selectivities, in addition to shorter …
Design, synthesis and ADMET prediction of bis-benzimidazole as anticancer agent
M Rashid - Bioorganic chemistry, 2020 - Elsevier
A new series of bis-benzimidazole clubbed with primary amine (3i-iii) and aromatic
aldehydes (4i-ix) were design and synthesize with an intention to search an anticancer lead …
aldehydes (4i-ix) were design and synthesize with an intention to search an anticancer lead …
[HTML][HTML] Benzimidazoles: A biologically active compounds
M Shaharyar, A Mazumder - Arabian Journal of Chemistry, 2017 - Elsevier
Synthesis of commercially available benzimidazole involves condensation of o-
phenylenediamine with formic acid. The most prominent benzimidazole compound in nature …
phenylenediamine with formic acid. The most prominent benzimidazole compound in nature …
Synthesis of benzimidazoles bearing oxadiazole nucleus as anticancer agents
Starting from 4-(1H-benzo [d] imidazol-2-yl)-4-oxobutanehydrazide (1), twenty new 1-(1H-
benzo [d] imidazol-2-yl)-3-(1, 3, 4-oxadiazol-5-substituted derivatives-2-yl) propan-1-ones …
benzo [d] imidazol-2-yl)-3-(1, 3, 4-oxadiazol-5-substituted derivatives-2-yl) propan-1-ones …
Recent advancements on benzimidazole: A versatile scaffold in medicinal chemistry
ZMM Alzhrani, MM Alam… - Mini Reviews in Medicinal …, 2022 - ingentaconnect.com
Benzimidazole is a nitrogen-containing fused heterocycle which has been extensively
explored in medicinal chemistry. Benzimidizole nucleus has been found to possess various …
explored in medicinal chemistry. Benzimidizole nucleus has been found to possess various …
Functionalized benzimidazole scaffolds: privileged heterocycle for drug design in therapeutic medicine
Benzimidazole derivatives are crucial structural scaffolds found in diverse libraries of
biologically active compounds which are therapeutically useful agents in drug discovery and …
biologically active compounds which are therapeutically useful agents in drug discovery and …
Microwave-assisted synthesis of N-heterocycles in medicinal chemistry
D Garella, E Borretto, A Di Stilo, K Martina… - …, 2013 - pubs.rsc.org
The syntheses of almost all N-heterocycles have now been successfully performed under
microwave irradiation and have provided significant improvements in the reaction time and …
microwave irradiation and have provided significant improvements in the reaction time and …