Vitamin A update: forms, sources, kinetics, detection, function, deficiency, therapeutic use and toxicity

A Carazo, K Macáková, K Matoušová, LK Krčmová… - Nutrients, 2021 - mdpi.com
Vitamin A is a group of vital micronutrients widely present in the human diet. Animal-based
products are a rich source of the retinyl ester form of the vitamin, while vegetables and fruits …

Homeostatic synaptic plasticity: local and global mechanisms for stabilizing neuronal function

G Turrigiano - Cold Spring Harbor perspectives in …, 2012 - cshperspectives.cshlp.org
Neural circuits must maintain stable function in the face of many plastic challenges,
including changes in synapse number and strength, during learning and development …

The structure, function and evolution of proteins that bind DNA and RNA

WH Hudson, EA Ortlund - Nature reviews Molecular cell biology, 2014 - nature.com
Proteins that bind both DNA and RNA typify the ability of a single gene product to perform
multiple functions. Such DNA-and RNA-binding proteins (DRBPs) have unique functional …

Vitamin A and retinoid signaling: genomic and nongenomic effects: thematic review series: fat-soluble vitamins: vitamin A

Z Al Tanoury, A Piskunov, C Rochette-Egly - Journal of lipid research, 2013 - ASBMB
Vitamin A or retinol is arguably the most multifunctional vitamin in the human body, as it is
essential from embryogenesis to adulthood. The pleiotropic effects of vitamin A are exerted …

Vitamin A and retinoic acid in cognition and cognitive disease

MU Wołoszynowska-Fraser… - Annual review of …, 2020 - annualreviews.org
The history of vitamin A goes back over one hundred years, but our realization of its
importance for the brain and cognition is much more recent. The brain is more efficient than …

HITS‐CLIP: panoramic views of protein–RNA regulation in living cells

RB Darnell - Wiley Interdisciplinary Reviews: RNA, 2010 - Wiley Online Library
The study of gene regulation in cells has recently begun to shift from a period dominated by
the study of transcription factor‐DNA interactions to a new focus on RNA regulation. This …

Retinoic acid and immune homeostasis: a balancing act

MN Erkelens, RE Mebius - Trends in immunology, 2017 - cell.com
In the immune system, the vitamin A metabolite retinoic acid (RA) is known for its role in
inducing gut-homing molecules in T and B cells, inducing regulatory T cells (Tregs), and …

Retinoic acid and retinoic acid receptors as pleiotropic modulators of the immune system

A Larange, H Cheroutre - Annual review of immunology, 2016 - annualreviews.org
Vitamin A is a multifunctional vitamin implicated in a wide range of biological processes. Its
control over the immune system and functions are perhaps the most pleiotropic not only for …

Retinoid pathway and cancer therapeutics

N Bushue, YJY Wan - Advanced drug delivery reviews, 2010 - Elsevier
The retinoids are a class of compounds that are structurally related to vitamin A. Retinoic
acid, which is the active metabolite of retinol, regulates a wide range of biological processes …

From carrot to clinic: an overview of the retinoic acid signaling pathway

M Theodosiou, V Laudet, M Schubert - Cellular and molecular life sciences, 2010 - Springer
Vitamin A is essential for the formation and maintenance of many body tissues. It is also
important for embryonic growth and development and can act as a teratogen at critical …