Disease gene discovery in male infertility: past, present and future
Identifying the genes causing male infertility is important to increase our biological
understanding as well as the diagnostic yield and clinical relevance of genetic testing in this …
understanding as well as the diagnostic yield and clinical relevance of genetic testing in this …
Esrrb, an estrogen‐related receptor involved in early development, pluripotency, and reprogramming
Estrogen‐related receptor b (Esrrb) is part of a family of three orphan nuclear receptors with
broad expression profiles and a generic function in regulating energy metabolism in …
broad expression profiles and a generic function in regulating energy metabolism in …
[HTML][HTML] Single-cell RNA-sequencing reveals the transcriptional landscape of ND-42 mediated spermatid elongation via mitochondrial derivative maintenance in …
J Yu, Z Li, Y Fu, F Sun, X Chen, Q Huang, L He, H Yu… - Redox Biology, 2023 - Elsevier
During spermatogenesis, mitochondria extend along the whole length of spermatid tail and
offer a structural platform for microtubule reorganization and synchronized spermatid …
offer a structural platform for microtubule reorganization and synchronized spermatid …
A RNA-Seq analysis to describe the boar sperm transcriptome and its seasonal changes
Understanding the molecular basis of cell function and ultimate phenotypes is crucial for the
development of biological markers. With this aim, several RNA-seq studies have been …
development of biological markers. With this aim, several RNA-seq studies have been …
Major spliceosome defects cause male infertility and are associated with nonobstructive azoospermia in humans
H Wu, L Sun, Y Wen, Y Liu, J Yu… - Proceedings of the …, 2016 - National Acad Sciences
Processing of pre-mRNA into mRNA is an important regulatory mechanism in eukaryotes
that is mediated by the spliceosome, a huge and dynamic ribonucleoprotein complex …
that is mediated by the spliceosome, a huge and dynamic ribonucleoprotein complex …
Structure and molecular basis of spermatid elongation in the Drosophila testis
Q Huang, X Chen, H Yu, L Ji, Y Shi… - Open …, 2023 - royalsocietypublishing.org
Spermatid elongation is a crucial event in the late stage of spermatogenesis in the
Drosophila testis, eventually leading to the formation of mature sperm after meiosis. During …
Drosophila testis, eventually leading to the formation of mature sperm after meiosis. During …
A chromosome-level assembly supports genome-wide investigation of the DMRT gene family in the golden mussel (Limnoperna fortunei)
JG RN Ferreira, J A. Americo, D LAS do Amaral… - …, 2023 - academic.oup.com
Abstract Background The golden mussel (Limnoperna fortunei) is a highly invasive species
that causes environmental and socioeconomic losses in invaded areas. Reference …
that causes environmental and socioeconomic losses in invaded areas. Reference …
[HTML][HTML] The big bang of genome editing technology: development and application of the CRISPR/Cas9 system in disease animal models
S Ming, XU Tian-Rui, C Ce-Shi - Zoological Research, 2016 - ncbi.nlm.nih.gov
Targeted genome editing technology has been widely used in biomedical studies. The
CRISPR-associated RNA-guided endonuclease Cas9 has become a versatile genome …
CRISPR-associated RNA-guided endonuclease Cas9 has become a versatile genome …
Protein synthesis and degradation are essential to regulate germline stem cell homeostasis in Drosophila testes
J Yu, X Lan, X Chen, C Yu, Y Xu, Y Liu, L Xu… - …, 2016 - journals.biologists.com
The homeostasis of self-renewal and differentiation in stem cells is controlled by intrinsic
signals and their niche. We conducted a large-scale RNA interference (RNAi) screen in …
signals and their niche. We conducted a large-scale RNA interference (RNAi) screen in …
Genetic factors influencing sperm competition
A Civetta, JM Ranz - Frontiers in genetics, 2019 - frontiersin.org
Females of many different species often mate with multiple males, creating opportunities for
competition among their sperm. Although originally unappreciated, sperm competition is …
competition among their sperm. Although originally unappreciated, sperm competition is …