Psychedelics (serotonergic hallucinogens) are powerful psychoactive substances that alter
perception and mood and affect numerous cognitive processes. They are generally …

Psychedelics, also known as classical hallucinogens, have been investigated for decades
due to their potential therapeutic effects in the treatment of neuropsychiatric and substance …

Abstract Serotonergic hallucinogens, such as (+)-lysergic acid diethylamide, psilocybin, and
mescaline, are somewhat enigmatic substances. Although these drugs are derived from …

Serotonergic hallucinogens produce profound changes in perception, mood, and cognition.
These drugs include phenylalkylamines such as mescaline and 2, 5-dimethoxy-4 …

Major depressive disorder (MDD) is a heritable neuropsychiatric disease associated with
severe changes at cellular and molecular levels. Its diagnosis mainly relies on the …

Blockade of the serotonin 5-HT 2A G protein-coupled receptor (5-HT 2A R) is a fundamental
pharmacological characteristic of numerous antipsychotic medications, which are FDA …

In recent years, there have been huge advances in the use of genetically modified mice to
study pathophysiological mechanisms involved in schizophrenia. This has allowed rapid …

Two primary animal models persist for assessing hallucinogenic potential of novel
compounds and for examining the pharmacological and neurobiological substrates …

1-(2, 5-Dimethoxy-4-iodophenyl)-2-aminopropane (DOI, or DOX where X=− I) was first
synthesized in 1973 in a structure–activity study to explore the effect of various aryl …

Autism spectrum disorder (ASD) is a group of neurodevelopmental disorders characterized
by repetitive and stereotyped behaviors as well as difficulties with social interaction and …