▪ Abstract The inheritance of mitochondrial and chloroplast genes differs from that of nuclear
genes in showing vegetative segregation, uniparental inheritance, intracellular selection …

It is generally assumed that mitochondrial genomes are uniparentally transmitted,
homoplasmic and nonrecombining. However, these assumptions draw largely from early …

Mammalian mtDNA is packaged in DNA-protein complexes denoted mitochondrial
nucleoids. The organization of the nucleoid is a very fundamental question in mitochondrial …

Ca2+ flux across the mitochondrial inner membrane regulates bioenergetics, cytoplasmic
Ca2+ signals and activation of cell death pathways,,,,,,,,,,. Mitochondrial Ca2+ uptake occurs …

Mutations spawn genetic variation which, in turn, fuels evolution. Hence, experimental
investigations into the rate and fitness effects of spontaneous mutations are central to the …

Mitochondrial DNA (mtDNA) is a pivotal tool in molecular ecology, evolutionary and
population genetics. The power of mtDNA analyses derives from a relatively high mutation …

Instability of the mitochondrial genome (mtDNA) is a general problem from yeasts to
humans. However, its genetic control is not well documented except in the yeast …

▪ Abstract Proteins that control mitochondrial dynamics in yeast are being identified at a
rapid pace. These proteins include cytoskeletal elements that regulate organelle distribution …

In the yeast Saccharomyces cerevisiae, mitochondria form a branched, tubular reticulum in
the periphery of the cell. Mmm1p is required to maintain normal mitochondrial shape and in …

The proper functioning of the cell depends on preserving the cellular genome. In yeast cells,
a limited number of genes are located on mitochondrial DNA. Although the mechanisms …