The importance of myosin motor protein is well-characterised within the cytoplasm and
cytoskeleton. However, mounting evidence on four nuclear myosins highlights the central …

The anchorage of Ras isoforms in the membrane and their nanocluster formations have
been studied extensively, including their detailed interactions, sizes, preferred membrane …

Mono-ubiquitinated PCNA (mono-Ub-PCNA) is generated when replication forks encounter
obstacles, enabling the bypass of DNA lesions. After resolving stalled forks, Ub-PCNA must …

The products synthesized by RNA polymerase I (Pol I) play fundamental roles in several
cellular processes, including ribosomal biogenesis, protein synthesis, cell metabolism, and …

Ribosomal transcription constitutes the major energy consuming process in cells and is
regulated in response to proliferation, differentiation and metabolic conditions by several …

The burden neurodegenerative diseases place on patients, their loved ones, and the
healthcare system is significant, and despite extensive research efforts, there is currently no …

Cell survival, growth, and proliferation are dependent on ribosomal protein synthesis.
Ribosome biogenesis is thus a highly regulated process to preserve cell function and …

The regulation of chromatin structure is fundamental to a wide range of cellular processes,
including transcriptional regulation, cell division, differentiation and DNA damage repair …

Loss of insulin-producing β cell numbers and/or function are the defining characteristics of
diabetes. Research on the cellular mechanisms that lead to these diseases is focused on …