Diagnosing and treating hypersomnolence in depression

C Moderie, DB Boivin - Sleep Medicine, 2024 - Elsevier
Hypersomnolence, a broad presentation encompassing excessive daytime sleepiness,
hypersomnia and sleep inertia, affects around 25% of patients with a major depressive …

The interface of depression and diabetes: treatment considerations

G Fanelli, E Raschi, G Hafez, S Matura… - Translational …, 2025 - nature.com
This state-of-the-art review explores the relationship between depression and diabetes,
highlighting the two-way influences that make treatment challenging and worsen the …

[HTML][HTML] IN Esketamine and IV ketamine: results of a multi-site observational study assessing the effectiveness and tolerability of two novel therapies for treatment …

G Gutierrez, J Swainson, N Ravindran, RW Lam… - Psychiatry …, 2024 - Elsevier
Intravenous (IV) ketamine and intranasal (IN) esketamine are novel therapies to manage
treatment resistant depression within major depressive disorder (MDD-TRD). This is a multi …

The gut-brain axis in depression: Are multi-omics showing the way?

JA Foster, MH Trivedi - Cell Reports Medicine, 2024 - cell.com
It is time for a paradigm shift in psychiatry. The need for biologically based models to
understand clinical heterogeneity is gaining momentum. Integrating the microbiome into …

[HTML][HTML] Effectiveness of sequential bilateral repetitive transcranial stimulation versus bilateral theta burst stimulation for patients with treatment-resistant depression …

M Wada, S Nakajima, K Taniguchi, S Honda, Y Mimura… - Brain stimulation, 2025 - Elsevier
Background Bilateral repetitive transcranial magnetic stimulation (BL-rTMS) over the
dorsolateral prefrontal cortex is effective for treatment-resistant depression (TRD). Owing to …

[HTML][HTML] Does the Digital Therapeutic Alliance Exist? Integrative Review

A Malouin-Lachance, J Capolupo, C Laplante… - JMIR Mental …, 2025 - mental.jmir.org
Background Mental health disorders significantly impact global populations, prompting the
rise of digital mental health interventions, such as artificial intelligence (AI)-powered …

Pharmacological treatment for mental health illnesses in adults receiving dialysis: A sco** review

J Wichart, P Yoeun, T Chin, C Evernden… - Fundamental & …, 2024 - Wiley Online Library
Background Pharmacologic management of mental health illnesses in patients receiving
dialysis is complex and lacking data. Objective Our objective was to synthesize published …

[HTML][HTML] Emerging Trends in Non-Invasive Brain Stimulation: The New Kids on the Block

AR Brunoni, PE Croarkin, LB Razza - Biomedicines, 2024 - mdpi.com
In the Sustainable Development Goals of the United Nations for 2030, mental health has
been identified as a global priority, emphasizing the need to reduce the prevalence …

[HTML][HTML] Improving the physical health of overweight/obese people suffering from severe mental disorders: What is the role of antipsychotic drugs and of lifestyle …

G Sampogna, M Di Vincenzo, M Luciano… - Journal of Psychiatric …, 2025 - Elsevier
People with severe mental disorders experience premature mortality compared with the
general population. Several factors contribute to the mortality gap, including the adoption of …

[HTML][HTML] Psychedelics and Suicide-Related Outcomes: A Systematic Review

S Meshkat, T Malik, R Zeifman, J Swainson… - Journal of Clinical …, 2025 - mdpi.com
Background/Objectives: Suicide accounts for 1.4% of global deaths, and the slow-acting
nature of traditional treatments for suicide risk underscores the need for alternatives …