The anorexia of ageing, a reduction in food intake with increased age, is associated with
negative health outcomes such as sarcopenia frailty, cachexia morbidity and mortality …

AgRP/NPY neurons are a discrete population with expression limited to the hypothalamic
arcuate nucleus. They are orexigenic, forming a critical component of the appetiteregulating …

Obesity is a global epidemic for which the current weight loss therapies are relatively
ineffective. Many central and peripheral factors are involved in the mechanisms controlling …