Breast cancer is a complex and diverse condition that disrupts multiple signaling pathways
essential for cell proliferation, survival, and differentiation. Recently, the significant …

Early growth response 1 (EGR1) is a multifunctional mammalian transcription factor capable
of both enhancing and/or inhibiting gene expression. EGR1 can be activated by a wide array …

Senescence plays a key role in various physiological and pathological processes. We
reported that injury-induced transient senescence correlates with heart regeneration, yet the …

Bacterial meningitis remains a leading cause of infection-related mortality worldwide.
Although Escherichia coli (E. coli) is the most common etiology of neonatal meningitis, the …

In mammalian somatic cells, the relative contribution of RNAi and the type I interferon
response during viral infection is unclear. The apparent inefficiency of antiviral RNAi might …

Anginosus group streptococci (AGS) are opportunistic human pathogens of the oral cavity.
The β-hemolytic subgroup of Streptococcus anginosus subsp. anginosus secretes …

The severe fever with thrombocytopenia syndrome virus (SFTSV) is a novel phlebovirus,
recently being officially renamed as Dabie bandavirus, and a causative agent for an …

Background Mycosis fungoides (MF), the most common cutaneous T-cell lymphoma, is often
underdiagnosed in early stages because of similarities with benign dermatoses such as …

Early transcription factors play critical roles in the development of acute lung injury/acute
respiratory distress syndrome (ALI/ARDS). Early growth response 1 (EGR1) is a transcription …

Macrophages are efficient reservoirs for viruses that enable the viruses to survive over a
longer period of infection. Alphaviruses such as chikungunya virus (CHIKV) are known to …