[HTML][HTML] Interplay between aging and other factors of the pathogenesis of age-related macular degeneration

J Blasiak, P Sobczuk, E Pawlowska… - Ageing Research …, 2022 - Elsevier
Highlights•Aging is the major risk factor for AMD.•The macula contains more than 60 kinds of
cells that may age at different rates.•The retinal aging in AMD is determined by its interplay …

Development of macular atrophy in patients with wet age-related macular degeneration receiving anti-VEGF treatment

A Foss, T Rotsos, T Empeslidis, V Chong - Ophthalmologica, 2022 - karger.com
Age-related macular degeneration (AMD) is a leading cause of blindness. Late AMD can be
classified into exudative (commonly known as wet AMD [wAMD]) or dry AMD, both of which …

Distribution and determinants of choroidal vascularity index in healthy eyes from deep-learning choroidal analysis: a population-based SS-OCT study

M Xuan, C Li, X Kong, J Zhang, W Wang… - British Journal of …, 2024 - bjo.bmj.com
Aims To quantify the profiles of choroidal vascularity index (CVI) using fully artificial
intelligence (AI)-based algorithm applied to swept-source optical coherence tomography …

Quantitative evaluation of the topographical maps of three-dimensional choroidal vascularity index in children with different degrees of myopia

F Liu, Y Ye, W Yang, J Wang, Y Xu… - … & Visual Science, 2024 - iovs.arvojournals.org
Purpose: To investigate topographical maps of the three-dimensional choroidal vascularity
index (3D-CVI) in children with different levels of myopia. Methods: We enrolled 274 eyes …

Accommodative movements of the choroid in the optic nerve head region of human eyes, and their relationship to the lens

MA Croft, J Peterson, C Smith, J Kiland, TM Nork… - Experimental eye …, 2022 - Elsevier
The ciliary muscle (CM) powers the accommodative response, and during accommodation
the CM pulls the choroid forward in the region of the ora serrata. Our goal was to elucidate …

Does senescence play a role in age-related macular degeneration?

G Malek, J Campisi, K Kitazawa, C Webster… - Experimental eye …, 2022 - Elsevier
Advanced age is the most established risk factor for develo** age-related macular
degeneration (AMD), one of the leading causes of visual impairment in the elderly, in …

Variability in retinal neuron populations and associated variations in mass transport systems of the retina in health and aging

MA Zouache - Frontiers in aging neuroscience, 2022 - frontiersin.org
Aging is associated with a broad range of visual impairments that can have dramatic
consequences on the quality of life of those impacted. These changes are driven by a …

Validation of reliability, repeatability and consistency of three-dimensional choroidal vascular index

F Ma, Y Bai, J Duan, Y Liang, Q Shang - Scientific Reports, 2024 - nature.com
This study aimed to investigate the reliability, repeatability and consistency of choroidal
vascularity index (CVI) measurements provided by an artificial intelligence-based software …

Aging in Ocular Blood Vessels: Molecular Insights and the Role of Oxidative Stress

X Cui, F Buonfiglio, N Pfeiffer, A Gericke - Biomedicines, 2024 - mdpi.com
Acknowledged as a significant pathogenetic driver for numerous diseases, aging has
become a focal point in addressing the profound changes associated with increasing human …

Age related grid-wise spatial analysis of choroidal parameters in well characterised healthy population

M Kumar, M Trinh, A Zhang, X Wei, R Agrawal… - Scientific Reports, 2024 - nature.com
Choroidal vascularity index (CVI) is an image-based metric applied to assess the choroid in
disease but poorly explored in natural aging. In this retrospective cohort study, we assessed …