Gliomas are the most common malignant primary brain tumours in adults and cannot usually
be cured with standard cancer treatments. Gliomas show intratumoural and intertumoural …

Abstract Purpose of Review Cerebral radiation necrosis (CRN) is a major dose-limiting
adverse event of radiotherapy. The incidence rate of RN varies with the radiotherapy …

Significance: Cancer cells are stabilized in an undifferentiated state similar to stem cells.
This leads to profound modifications of their metabolism, which further modifies their …

Cerebrospinal fluid (CSF) is a clear fluid circulating in the intracranial and spinal
compartments. Under normal conditions, the composition of CSF remains constant …

Medulloblastoma (MB) is the most common malignant brain tumor in children. There
remains an unmet need for diagnostics to sensitively detect the disease, particularly …

Gliomas, particularly glioblastoma (GBM), represent the most prevalent and aggressive
tumors of the central nervous system (CNS). Despite recent treatment advancements, patient …

Metabolic reprogramming has been suggested as a hallmark of cancer progression.
Metabolomic analysis of various metabolic profiles represents a powerful and technically …

The high morbidity and mortality of neuroinflammatory diseases drives significant interest in
understanding the underlying mechanisms involved in the innate and adaptive immune …

Gliomas are the most common type of malignant brain tumor and are characterized by a
plethora of heterogeneous molecular alterations. Current treatments require the emergence …

In recent years, liquid biopsy has emerged as an alternative method to diagnose and
monitor tumors. Compared to classical tissue biopsy procedures, liquid biopsy facilitates the …