Molecular probes, chemosensors, and nanosensors for optical detection of biorelevant molecules and ions in aqueous media and biofluids

J Krämer, R Kang, LM Grimm, L De Cola… - Chemical …, 2022 - ACS Publications
Synthetic molecular probes, chemosensors, and nanosensors used in combination with
innovative assay protocols hold great potential for the development of robust, low-cost, and …

Cardiovascular complications in chronic kidney disease: a review from the European Renal and Cardiovascular Medicine Working Group of the European Renal …

C Zoccali, F Mallamaci, M Adamczak… - Cardiovascular …, 2023 - academic.oup.com
Chronic kidney disease (CKD) is classified into five stages with kidney failure being the most
severe stage (stage G5). CKD conveys a high risk for coronary artery disease, heart failure …

Influence of the microbiome, diet and genetics on inter-individual variation in the human plasma metabolome

L Chen, DV Zhernakova, A Kurilshikov… - Nature medicine, 2022 - nature.com
The levels of the thousands of metabolites in the human plasma metabolome are strongly
influenced by an individual's genetics and the composition of their diet and gut microbiome …

Endothelial cell dysfunction and increased cardiovascular risk in patients with chronic kidney disease

CC Baaten, S Vondenhoff, H Noels - Circulation research, 2023 - ahajournals.org
The endothelium is considered to be the gatekeeper of the vessel wall, maintaining and
regulating vascular integrity. In patients with chronic kidney disease, protective endothelial …

[HTML][HTML] Classification of uremic toxins and their role in kidney failure

MH Rosner, T Reis, F Husain-Syed… - Clinical Journal of the …, 2021 - journals.lww.com
Advances in our understanding of uremic retention solutes, and improvements in
hemodialysis membranes and other techniques designed to remove uremic retention …

Oxalate homeostasis

T Ermer, L Nazzal, MC Tio, S Waikar… - Nature Reviews …, 2023 - nature.com
Oxalate homeostasis is maintained through a delicate balance between endogenous
sources, exogenous supply and excretion from the body. Novel studies have shed light on …

The impact of CKD on uremic toxins and gut microbiota

J Rysz, B Franczyk, J Ławiński, R Olszewski… - Toxins, 2021 - mdpi.com
Numerous studies have indicated that the progression of chronic kidney disease (CKD) to
end-stage renal disease (ESRD) is strictly associated with the accumulation of toxic …

Obstructive nephropathy and molecular pathophysiology of renal interstitial fibrosis

R Nørregaard, HAM Mutsaers, J Frøkiær… - Physiological …, 2023 - journals.physiology.org
The kidneys play a key role in maintaining total body homeostasis. The complexity of this
task is reflected in the unique architecture of the organ. Ureteral obstruction greatly affects …

Plant-based diets to manage the risks and complications of chronic kidney disease

JJ Carrero, A González-Ortiz, CM Avesani… - Nature Reviews …, 2020 - nature.com
Traditional dietary recommendations for patients with chronic kidney disease (CKD) focus
on the quantity of nutrients consumed. Without appropriate dietary counselling, these …

Uremic toxins in the progression of chronic kidney disease and cardiovascular disease: mechanisms and therapeutic targets

YJ Lim, NA Sidor, NC Tonial, A Che, BL Urquhart - Toxins, 2021 - mdpi.com
Chronic kidney disease (CKD) is a progressive loss of renal function. The gradual decline in
kidney function leads to an accumulation of toxins normally cleared by the kidneys, resulting …