Chikungunya fever

K Bartholomeeusen, M Daniel, DA LaBeaud… - Nature Reviews …, 2023 - nature.com
Chikungunya virus is widespread throughout the tropics, where it causes recurrent
outbreaks of chikungunya fever. In recent years, outbreaks have afflicted populations in East …

Nanotechnology's frontier in combatting infectious and inflammatory diseases: prevention and treatment

Y Huang, X Guo, Y Wu, X Chen, L Feng, N **e… - … and Targeted Therapy, 2024 - nature.com
Inflammation-associated diseases encompass a range of infectious diseases and non-
infectious inflammatory diseases, which continuously pose one of the most serious threats to …

Clinical delivery of circular RNA: lessons learned from RNA drug development

TL Young, KC Wang, AJ Varley, B Li - Advanced drug delivery reviews, 2023 - Elsevier
Circular RNAs (circRNA) represent a distinct class of covalently closed-loop RNA molecules,
which play diverse roles in regulating biological processes and disease states. The …

Progress and prospects on vaccine development against monkeypox infection

MJ Saadh, T Ghadimkhani, N Soltani… - Microbial …, 2023 - Elsevier
The monkeypox virus (MPOX) is an uncommon zoonotic illness brought on by an
orthopoxvirus (OPXV). MPOX can occur with symptoms similar to smallpox. Since April 25 …

Virus-like particles as nanocarriers for intracellular delivery of biomolecules and compounds

J He, L Yu, X Lin, X Liu, Y Zhang, F Yang, W Deng - Viruses, 2022 - mdpi.com
Virus-like particles (VLPs) are nanostructures assemble from viral proteins. Besides widely
used for vaccine development, VLPs have also been explored as nanocarriers for cargo …

Virus‐like particles as powerful vaccination strategy against human viruses

I Hadj Hassine, M Ben M'hadheb… - Reviews in Medical …, 2024 - Wiley Online Library
Nowadays, viruses are not only seen as causative agents of viral infectious diseases but
also as valuable research materials for various biomedical purposes, including recombinant …

[HTML][HTML] Integrating immunopeptidome analysis for the design and development of cancer vaccines

S Feola, J Chiaro, V Cerullo - Seminars in immunology, 2023 - Elsevier
The repertoire of naturally presented peptides within the MHC (major histocompatibility
complex) or HLA (human leukocyte antigens) system on the cellular surface of every …

The potential of gene editing for Huntington's disease

W Duan, E Urani, MP Mattson - Trends in neurosciences, 2023 - cell.com
Huntington's disease (HD) is a dominantly inherited neurodegenerative disorder caused by
a trinucleotide repeat expansion in the huntingtin gene resulting in long stretches of …

Bacteriophage T4 as a Protein-Based, Adjuvant-and Needle-Free, Mucosal Pandemic Vaccine Design Platform

J Zhu, P Tao, AK Chopra, VB Rao - Annual Review of Virology, 2024 - annualreviews.org
The COVID-19 pandemic has transformed vaccinology. Rapid deployment of mRNA
vaccines has saved countless lives. However, these platforms have inherent limitations …

Hantavirus: an overview and advancements in therapeutic approaches for infection

S Afzal, L Ali, A Batool, M Afzal, N Kanwal… - Frontiers in …, 2023 - frontiersin.org
Hantaviruses are a significant and emerging global public health threat, impacting more
than 200,000 individuals worldwide each year. The single-stranded RNA viruses belong to …