Sensitive and specific antemortem biomarkers of neurodegenerative disease and dementia
are crucial to the pursuit of effective treatments, required both to reliably identify disease and …

Alzheimer disease (AD) is the most common cause of dementia in the elderly. Autopsy case
series on the sequential accumulation of neurofibrillary bundles and amyloid plaques, as …

It has been ascertained that the human brain is a complex system studied at multiple scales,
from neurons and microcircuits to macronetworks. The brain is characterized by a …

Altered cortical surface complexity and gyrification differences may be a potentially sensitive
marker for several neurodevelopmental disorders. We propose to use spherical harmonic …

Fractal analysis methods are used to quantify the complexity of the human cerebral cortex.
Many recent studies have focused on high resolution three-dimensional reconstructions of …

Purpose: The main purpose of this study was to comprehensively investigate the potential of
fractal dimension (FD) measures in discriminating brain gliomas into low-grade glioma …

Fractal geometry has recently been proposed as a useful tool for characterizing the
complexity of the brain cortex, which is likely to derive from the recurrence of sulci–gyri …

The purpose of this project is to apply a modified fractal analysis technique to high-
resolution T1 weighted magnetic resonance images in order to quantify the alterations in the …

The fractal dimension (FD) is a quantitative parameter that characterizes the morphometric
variability of a complex object. Among other applications, FD has been used to identify …

In the search for a useful parameter to detect and quantify subtle brain abnormalities in
infants with intrauterine growth restriction (IUGR), we hypothesised that the analysis of the …