New insights into functional roles of the polypyrimidine tract-binding protein

MG Romanelli, E Diani, PMJ Lievens - International journal of molecular …, 2013 - mdpi.com
Polypyrimidine Tract Binding Protein (PTB) is an intensely studied RNA binding protein
involved in several post-transcriptional regulatory events of gene expression. Initially …

The emerging role of the RBM20 and PTBP1 ribonucleoproteins in heart development and cardiovascular diseases

S Fochi, P Lorenzi, M Galasso, C Stefani, E Trabetti… - Genes, 2020 - mdpi.com
Alternative splicing is a regulatory mechanism essential for cell differentiation and tissue
organization. More than 90% of human genes are regulated by alternative splicing events …

Protein kinase A phosphorylation modulates transport of the polypyrimidine tract-binding protein

J **e, JA Lee, TL Kress, KL Mowry… - Proceedings of the …, 2003 - National Acad Sciences
The heterogeneous nuclear ribonucleoprotein particle (hnRNP) proteins play important
roles in mRNA processing in eukaryotes, but little is known about how they are regulated by …

Functional analysis of the structural domain of ARF proteins in rice (Oryza sativa L.)

CJ Shen, SK Wang, YH Bai, YR Wu… - Journal of …, 2010 - academic.oup.com
Auxin response factors (ARFs) are key regulators of plant growth and development. Through
interaction with auxin/indole acetic acid (Aux/IAA) proteins, they influence the expression of …

NF-κB p52, RelB and c-Rel are transported into the nucleus via a subset of importin α molecules

R Fagerlund, K Melén, X Cao, I Julkunen - Cellular signalling, 2008 - Elsevier
In resting cells NF-κB transcription factors are retained in the cytoplasm as latent inactive
complexes, until they are activated and rapidly transported into the nucleus. We show that all …

Constitutive nuclear import and stress‐regulated nucleocytoplasmic shuttling of mammalian heat‐shock factor 1

M Vujanac, A Fenaroli, V Zimarino - Traffic, 2005 - Wiley Online Library
Inducible expression of major cytosolic and nuclear chaperone proteins is mediated by the
heat‐shock transcription factor HSF1 that is activated by derepressive mechanisms triggered …

[HTML][HTML] Relocalization of the polypyrimidine tract-binding protein during PKA-induced neurite growth

S Ma, G Liu, Y Sun, J **e - Biochimica et Biophysica Acta (BBA)-Molecular …, 2007 - Elsevier
Neurite RNA binding proteins are important for neurite growth, a process critical for neuronal
development and regeneration after injury. It has been known that many RNA binding …

Post-translational modifications in polypyrimidine tract binding proteins PTBP1 and PTBP2

JM Pina, JM Reynaga, AAM Truong… - Biochemistry, 2018 - ACS Publications
RNA binding proteins play an important role in regulating alternative pre-mRNA splicing and
in turn cellular gene expression. Many of these RNA binding proteins occur as gene families …

A functional nuclear localization signal in insulin-like growth factor binding protein-6 mediates its nuclear import

C Iosef, T Gkourasas, CYH Jia, SSC Li… - Endocrinology, 2008 - academic.oup.com
IGF binding protein (IGFBP)-6 is a member of the IGFBP family that regulates the actions of
IGFs. Although IGFBPs exert their functions extracellularly in an autocrine/paracrine manner …

Identification of nuclear localization signal that governs nuclear import of BRD7 and its essential roles in inhibiting cell cycle progression

M Zhou, H Liu, X Xu, H Zhou, X Li… - Journal of cellular …, 2006 - Wiley Online Library
BRD7, a novel bromodomain gene, is identified to be associated with nasopharyngeal
carcinoma (NPC). Decreased or loss of expression of BRD7 was detected in NPC biopsies …