Extracellular vesicles in cancer—implications for future improvements in cancer care

R Xu, A Rai, M Chen, W Suwakulsiri… - Nature reviews Clinical …, 2018 - nature.com
The sustained growth, invasion, and metastasis of cancer cells depend upon bidirectional
cell–cell communication within complex tissue environments. Such communication …

Extracellular vesicle isolation and characterization: toward clinical application

R Xu, DW Greening, HJ Zhu, N Takahashi… - The Journal of clinical …, 2016 - jci.org
Two broad categories of extracellular vesicles (EVs), exosomes and shed microvesicles
(sMVs), which differ in size distribution as well as protein and RNA profiles, have been …

Evidence-based clinical use of nanoscale extracellular vesicles in nanomedicine

S Fais, L O'Driscoll, FE Borras, E Buzas, G Camussi… - Perspective, 2016 - ACS Publications
Recent research has demonstrated that all body fluids assessed contain substantial
amounts of vesicles that range in size from 30 to 1000 nm and that are surrounded by …

MicroRNA cargo of extracellular vesicles from alcohol-exposed monocytes signals naive monocytes to differentiate into M2 macrophages

B Saha, F Momen-Heravi, K Kodys, G Szabo - Journal of Biological …, 2016 - jbc.org
Membrane-coated extracellular vesicles (EVs) released by cells can serve as vehicles for
delivery of biological materials and signals. Recently, we demonstrated that alcohol-treated …

Understanding extracellular vesicle diversity–current status

DW Greening, RJ Simpson - Expert review of proteomics, 2018 - Taylor & Francis
ABSTRACT Introduction: Extracellular vesicles (EVs) represent an important mode of
intercellular communication. There is now a growing awareness that predominant EV …

Toxoplasmosis in human and animals around the world. Diagnosis and perspectives in the one health approach

RAM de Barros, AC Torrecilhas, MAM Marciano… - Acta tropica, 2022 - Elsevier
Toxoplasmosis is a unique health disease that significantly affects the health of humans,
domestic animals, wildlife and is present in ecosystems, including water, soil and food …

Guidelines for the purification and characterization of extracellular vesicles of parasites

C Fernandez‐Becerra, P Xander… - Journal of …, 2023 - Wiley Online Library
Parasites are responsible for the most neglected tropical diseases, affecting over a billion
people worldwide (WHO, 2015) and accounting for billions of cases a year and responsible …

Communication is key: extracellular vesicles as mediators of infection and defence during host–microbe interactions in animals and plants

H U. Stotz, D Brotherton, J Inal - FEMS microbiology reviews, 2022 - academic.oup.com
Extracellular vesicles (EVs) are now understood to be ubiquitous mediators of cellular
communication. In this review, we suggest that EVs have evolved into a highly regulated …

Extracellular vesicles in trypanosomatids: host cell communication

AC Torrecilhas, RP Soares, S Schenkman… - Frontiers in cellular …, 2020 - frontiersin.org
Trypanosoma cruzi, Trypanosoma brucei and Leishmania (Trypanosomatidae:
Kinetoplastida) are parasitic protozoan causing Chagas disease, African Trypanosomiasis …

The role of extracellular vesicles from different origin in the microenvironment of head and neck cancers

C **e, N Ji, Z Tang, J Li, Q Chen - Molecular cancer, 2019 - Springer
The proliferation and metastasis ability of tumors are mediate by the" mutual dialogue"
between cells in the tumor microenvironment (TME). Extracellular vesicles (EVs), mainly …