Background and Purpose—This scientific statement provides an overview of the evidence
on vascular contributions to cognitive impairment and dementia. Vascular contributions to …

Senescence is a leading cause of mortality, disability, and non‐communicable chronic
diseases in older adults. Mounting evidence indicates that the presence of cardiovascular …

Aims/Hypothesis Accumulating evidence suggests an association between coronary heart
disease and risk for cognitive impairment or dementia, but no study has systematically …

Cerebral blood flow (CBF) is rigorously regulated by various powerful mechanisms to
safeguard the match between cerebral metabolic demand and supply. The question of how …

Abstract The Montreal Cognitive Assessment (MoCA) is a cognitive screening instrument
developed to detect mild cognitive impairment (MCI). It is a simple 10 min paper and pencil …

Background and aim. During ageing, the prevalence of dementia, and especially of
Alzheimer's disease (AD) and cardiovascular disease (CVD), increases. The aim of this …

Prior studies have demonstrated decreasing cerebral blood flow (CBF) in normal aging, but
the full spatial pattern and potential mechanism of changes in CBF remain to be elucidated …

Heart failure (HF) is a complex clinical syndrome with multiple interactions between the
failing myocardium and cerebral (dys‐) functions. Bi‐directional feedback interactions …

Abstract Background and Purpose Cognitive decline is an important contributor to disability
in patients with chronic heart failure, affecting 25%–50% of patients. The aim of this review is …

As life expectancy lengthens, dementia is becoming a significant human condition in terms
of its prevalence and cost to society worldwide. It is important in that context to understand …