Bioengineering artificial blood vessels from natural materials

MJ Moore, RP Tan, N Yang, J Rnjak-Kovacina… - Trends in …, 2022 - cell.com
Bioengineering an effective, small diameter (< 6 mm) artificial vascular graft for use in
bypass surgery when autologous grafts are unavailable remains a persistent challenge …

[HTML][HTML] History, progress and future challenges of artificial blood vessels: A narrative review

K Hu, Y Li, Z Ke, H Yang, C Lu, Y Li, Y Guo… - Biomaterials …, 2022 - ncbi.nlm.nih.gov
Cardiovascular disease serves as the leading cause of death worldwide, with stenosis,
occlusion, or severe dysfunction of blood vessels being its pathophysiological mechanism …

Long-term sustained drug delivery via 3D printed masks for the development of a heparin-loaded interlayer in vascular tissue engineering applications

M Kimicata, B Mahadik, JP Fisher - ACS Applied Materials & …, 2021 - ACS Publications
Current approaches in small-diameter vascular grafts for coronary artery bypass surgeries
fail to address physiological variations along the graft that contribute to thrombus formation …

Strategies to counteract adverse remodeling of vascular graft: A 3D view of current graft innovations

W Tan, P Boodagh, PP Selvakumar… - … in Bioengineering and …, 2023 - frontiersin.org
Vascular grafts are widely used for vascular surgeries, to bypass a diseased artery or
function as a vascular access for hemodialysis. Bioengineered or tissue-engineered …

Nanomaterials for small diameter vascular grafts: overview and outlook

N Wang, H Wang, D Weng, Y Wang, L Yu… - Nanoscale …, 2023 - pubs.rsc.org
Small-diameter vascular grafts (SDVGs) cannot meet current clinical demands owing to their
suboptimal long-term patency rate. Various materials have been employed to address this …

Electrospun PCL/collagen hybrid nanofibrous tubular graft based on post-network bond processing for vascular substitute

W Ma, L Wang, Q Zhang, X Dong, T Zhu, S Lu - Biomaterials Advances, 2022 - Elsevier
Inhibiting thrombus formation and intimal hyperplasia is essential for orthotopic tissue-
engineered vascular grafts. The matching mechanical properties of autologous blood …

Effects of weaving parameters on the properties of completely biological tissue-engineered vascular grafts

G Roudier, M Hourques, N Da Silva, M Gluais… - …, 2023 - iopscience.iop.org
Tissue-engineered vascular grafts (TEVGs) made of human textiles have been recently
introduced and offer remarkable biocompatibility as well as tunable mechanical properties …

Decellularized Extracellular Matrix and Polyurethane Vascular Grafts Have Positive Effects on the Inflammatory and Pro‐Thrombotic State of Aged Endothelial Cells

SJ Specht, S Rohringer, P Hager… - … Research Part A, 2025 - Wiley Online Library
In vitro assessment of small‐diameter synthetic vascular grafts usually uses standard cell
culture conditions with early‐passage cells. However, these conduits are mainly implanted …

Human Adipose-Derived Mesenchymal Stem Cell-Secreted Extracellular Matrix Coating on a Woven Nanotextile Vascular Patch for Improved Endothelial Cell …

K Gopal, N Nandakumar, R CR, R Babu… - ACS Applied Bio …, 2023 - ACS Publications
Biomedical implants possessing the structural and functional characteristics of extracellular
matrix (ECM) are pivotal for vascular applications. This study investigated the potential of …

Adipose-derived stem cells significantly increases collagen level and fiber maturity in patient-specific biological engineered blood vessels

BT Wonski, B Patel, DG Tepper, A Siddiqui… - Plos one, 2023 - journals.plos.org
Tissue engineering has driven significant research in the strive to create a supply of tissues
for patient treatment. Cell integration into engineered tissues maximizes functional …